Val-cit-PAB-OH

Val-cit-PAB-OH Structure
CAS No.
159857-79-1
Chemical Name:
Val-cit-PAB-OH
Synonyms
H-Val-Cit-PAB-OH;(S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide;EOS-61316;al-Cit-PAB-OH;H-Val-Cit-PAB;Val-cit-PAB-OH;(D)-VAL-CIT-PAB;NH2-Val-Cit-PAB;2-(4-(((2,6-dimethylbenzoyl)oxy)methyl)phenyl)aceticacid;L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide
CBNumber:
CB92715206
Molecular Formula:
C18H29N5O4
Molecular Weight:
379.45
MOL File:
159857-79-1.mol
Modify Date:
2024/3/29 16:09:00

Val-cit-PAB-OH Properties

Melting point 168 °C(dec.)
Boiling point 715.0±60.0 °C(Predicted)
Density 1.243±0.06 g/cm3(Predicted)
storage temp. 2-8°C(protect from light)
solubility DMF: 10 mg/ml; DMSO: 10 mg/ml; PBS (pH 7.2): 1 mg/ml
form powder to crystal
pka 13.75±0.46(Predicted)
color White to Almost white

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H315-H335-H319-H302
Precautionary statements  P264-P280-P302+P352-P321-P332+P313-P362-P264-P270-P301+P312-P330-P501-P264-P280-P305+P351+P338-P337+P313P
HS Code  2924.29.7790
NFPA 704
0
2 0

Val-cit-PAB-OH price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemicals (India) V0155 Val-Cit-PAB-OH 159857-79-1 25MG ₹4700 2022-05-26 Buy
TCI Chemicals (India) V0155 Val-Cit-PAB-OH 159857-79-1 100MG ₹8800 2022-05-26 Buy
Product number Packaging Price Buy
V0155 25MG ₹4700 Buy
V0155 100MG ₹8800 Buy

Val-cit-PAB-OH Chemical Properties,Uses,Production

Uses

Val-cit-PAB-OH acts as a reagent in the preparation of cell-penetrating peptidic GRP78 ligand for tumor cell-specific prodrug therapy, preparation of monomethylvaline derivative conjugates with ligands and antibodies for cancer treatment.

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(S)-2-((R)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide Val-cit-PAB-OH L-Valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]-L-ornithinamide EOS-61316 L-Ornithinamide, L-valyl-N5-(aminocarbonyl)-N-[4-(hydroxymethyl)phenyl]- NH2-Val-Cit-PAB (D)-VAL-CIT-PAB al-Cit-PAB-OH (S)-2-((S)-2-amino-3-methylbutanamido)-N-(4-(hydroxymethyl)phenyl)-5-ureidopentanamide H-Val-Cit-PAB-OH 2-(4-(((2,6-dimethylbenzoyl)oxy)methyl)phenyl)aceticacid H-Val-Cit-PAB (2S)-2-[[(2S)-2-amino-3-methyl-butanoyl]amino]-N-[4-(hydroxymethyl)phenyl]-5-ureido-pentanamide 159857-79-1 Linker ADC LINKER ADCs ADC-Linkers