((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate

((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate Structure
CAS No.
864070-37-1
Chemical Name:
((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate
Synonyms
(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;Empagliflozin-4;Dapagliflozin-009;Jardiance Impurity H;Daglitele Impurity 6;Epaliflozin Ipurity 5;Dapagliflozin Impurity L;Empagliflozin impurity H;Empagliflozin Impurity 5;Dapagliflozin O-Desethyl Impurity
CBNumber:
CB92728624
Molecular Formula:
C19H21ClO6
Molecular Weight:
380.82
MOL File:
864070-37-1.mol
Modify Date:
2024/5/20 18:13:44

((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate Properties

Boiling point 628.3±55.0 °C(Predicted)
Density 1.459±0.06 g/cm3(Predicted)
storage temp. -20°C
solubility DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
form A crystalline solid
pka 10.17±0.15(Predicted)
Stability Hygroscopic

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07,GHS08,GHS09
Signal word  Danger
Hazard statements  H302-H319-H372-H411
Precautionary statements  P260-P264-P270-P273-P280-P301+P312+P330-P305+P351+P338-P314-P337+P313-P391-P501

((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate Chemical Properties,Uses,Production

Uses

O-Desethyl Dapagliflozin is derivative of antidiabetic drug Dapagliflozin (D185370), which is sodium-glucose transporter 2 inhibitor.

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Empagliflozin impurity H Dapagliflozin Impurity L Empagliflozin-4 Dapagliflozin impurity 12/ O-Desethyl Dapagliflozin/(3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol Daglitele Impurity 6 D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-, (1S)- Jardiance Impurity H (3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol Dapagliflozin O-Desethyl Impurity Empagliflozin Destetrahydrofuran Impurity Empagliflozin Destetrahydrofuran ImpurityQ: What is Empagliflozin Destetrahydrofuran Impurity Q: What is the CAS Number of Empagliflozin Destetrahydrofuran Impurity Q: What is the storage condition of Empagliflozin Destetrahydrofuran Impurity Q: What are the applications of Empagliflozin Destetrahydrofuran Impurity (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol Dapagliflozin-009 Epaliflozin Ipurity 5 1-Chloro-4-(beta-D-glucopyranos-1-yl)-2-(4-hydroxybenzyl)-benzene (1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-D-glucitol Empagliflozin Impurity 5 864070-37-1