CETEARYL ALCOHOL
- CAS No.
- 8005-44-5
- Chemical Name:
- CETEARYL ALCOHOL
- Synonyms
- CETOSTEARYL ALCOHOL;C16-18;CETYLSTEARYL ALCOHOL;206-155-2;DEHYQUARTD;LANETTE AOK;BASF CSA 50;BASF CSA 70;Crodacol CS90;Kolliwax CSA 70
- CBNumber:
- CB9296156
- Molecular Formula:
- C16H34O
- Molecular Weight:
- 242.440002441406
- MOL File:
- 8005-44-5.mol
- MSDS File:
- SDS
- Modify Date:
- 2024/7/24 17:31:20
| solubility | Soluble in ethanol (95%), ether, and oil; practically insoluble in water. |
|---|---|
| InChI | InChI=1S/C18H38O.C16H34O/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19;1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17/h19H,2-18H2,1H3;17H,2-16H2,1H3 |
| InChIKey | UBHWBODXJBSFLH-UHFFFAOYSA-N |
| SMILES | C(O)CCCCCCCCCCCCCCC.C(O)CCCCCCCCCCCCCCCCC |
| CAS DataBase Reference | 8005-44-5(CAS DataBase Reference) |
CETEARYL ALCOHOL Chemical Properties,Uses,Production
Chemical Properties
Cetostearyl alcohol occurs as white or cream-colored unctuous masses, flakes, pellets or granules. It has a faint, characteristic sweet odor. On heating, cetostearyl alcohol melts to a clear, colorless or pale yellow-colored liquid free of suspended matter.
Production Methods
Cetostearyl alcohol is prepared by the reduction of the appropriate fatty acids from vegetable and animal sources. Cetostearyl alcohol can also be prepared directly from hydrocarbon sources.
Pharmaceutical Applications
Cetostearyl alcohol is used in cosmetics and topical pharmaceutical preparations. In topical pharmaceutical formulations, cetostearyl alcohol will increase the viscosity and act as an emulsifier in both water-in-oil and oil-in-water emulsions. Cetostearyl alcohol will stablize an emulsion and also act as a co-emulsifier, thus decreasing the total amount of surfactant required to form a stable emulsion. Cetostearyl alcohol is also used in the preparation of nonaqueous creams and sticks, and in nonlathering shaving creams. Research articles have been published in which cetostearyl alcohol has been used to control or slow the dissolution rate of tablets or microspheres containing water-soluble drugs, or poorly watersoluble drugs, as well as to stabilize amorphous systems. In combination with other surfactants, cetostearyl alcohol forms emulsions with very complex microstructures. These microstructures can include liquid crystals, lamellar structures, and gel phases.
Safety
Cetostearyl alcohol is mainly used in topical pharmaceutical
formulations and topical cosmetic formulations.
Cetostearyl alcohol is generally regarded as a nontoxic
material. Although it is essentially nonirritating, sensitization
reactions to cetostearyl, cetyl, and stearyl alcohols have been
reported.
Gamma radiation has been shown to be feasible for sterilization
of petrolatum containing cetostearyl alcohol resulting in low levels
of radiolysis products, which are of low toxicity.
storage
Cetostearyl alcohol is stable under normal storage conditions. Cetostearyl alcohol should be stored in a well-closed container in a cool, dry place.
Incompatibilities
Incompatible with strong oxidizing agents and metal salts.
Regulatory Status
Accepted as an indirect food additive and as an adhesive and a component of packaging coatings in the USA. Included in the FDA Inactive Ingredients Database (oral tablets; topical emulsions, lotions, ointments; vaginal suppositories). Included in nonparenteral medicines licensed in the UK. Included in the Canadian List of Acceptable Non-medicinal Ingredients.
CETEARYL ALCOHOL Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | Inquiry |
|---|---|---|---|---|---|
| PERFECT CHEMICAL | +91-9820465461 +91-9820465461 | Mumbai, India | 391 | 58 | Inquiry |
| Murli Krishna Exports Pvt Ltd | +91-2225631595 +91-2225631594 | New Delhi, India | 185 | 58 | Inquiry |
| ALPHA CHEMIKA | +91-22-22061123 +91-22-66382501 | Mumbai, India | 1681 | 43 | Inquiry |
| Scientific OEM | +91-22- 2343 7546 / 2341 3094 | New Delhi, India | 1996 | 38 | Inquiry |
| Sisco Research Laboratories Pvt. Ltd. | +91-22-4268 5800 | Mumbai, India | 4317 | 58 | Inquiry |
| Central Drug House(P) Ltd. | 91-11-49404040 | New Delhi, India | 6160 | 58 | Inquiry |
| Triveni chemicals | 08048762458 | New Delhi, India | 6093 | 58 | Inquiry |
| Magus Organochem | 08048372680Ext 461 | Delhi, India | 8 | 58 | Inquiry |
| Camex Speciality Private Limited | 08046051668 | Ahmedabad, India | 117 | 58 | Inquiry |
| Vardhman Enterprise | 08048950769 | Mumbai, India | 61 | 58 | Inquiry |
| Supplier | Advantage |
|---|---|
| PERFECT CHEMICAL | 58 |
| Murli Krishna Exports Pvt Ltd | 58 |
| ALPHA CHEMIKA | 43 |
| Scientific OEM | 38 |
| Sisco Research Laboratories Pvt. Ltd. | 58 |
| Central Drug House(P) Ltd. | 58 |
| Triveni chemicals | 58 |
| Magus Organochem | 58 |
| Camex Speciality Private Limited | 58 |
| Vardhman Enterprise | 58 |
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