2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Structure
CAS No.
682775-70-8
Chemical Name:
2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid
Synonyms
Epalrestat Methyl Ester;Naphthoic Acid Impurity 24;CGICFPQGDMJAMH-YGOOLXEZSA-N;Epalrestat (Z,Z)-Isomer Methyl Ester;2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid;3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-, methyl ester
CBNumber:
CB93353531
Molecular Formula:
C16H15NO3S2
Molecular Weight:
333.43
MOL File:
682775-70-8.mol
Modify Date:
2023/5/15 10:43:58

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Properties

Boiling point 472.1±55.0 °C(Predicted)
Density 1.34±0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Ethyl Acetate (Slightly)
form Solid
pka -3.51±0.20(Predicted)
color Yellow

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Chemical Properties,Uses,Production

Uses

(Z,Z)-Epalrestat Methyl Ester is a stereoisomer of Epalrestat (E565300), an aldose reductase inhibitor. Used in the treatment of diabetic neuropathy.

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Preparation Products And Raw materials

Raw materials

Preparation Products

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid Suppliers

2-((E)-5-((Z)-3-methyl-4-phenylbut-3-enylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid CGICFPQGDMJAMH-YGOOLXEZSA-N 3-Thiazolidineacetic acid, 5-(2-methyl-3-phenyl-2-propen-1-ylidene)-4-oxo-2-thioxo-, methyl ester Epalrestat Methyl Ester Epalrestat (Z,Z)-Isomer Methyl Ester Naphthoic Acid Impurity 24 682775-70-8