Oxo Enzalutamide

Oxo Enzalutamide Structure
CAS No.
1242137-18-3
Chemical Name:
Oxo Enzalutamide
Synonyms
Oxo Enzalutamide;Enzalutamide Impurities5;Enzalutamide Impurities750;Enzalutamide Impurity J/ Enzalutamide Oxo Impurity;4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide;Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methyl-;4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide? (Enzalutamide Impurity)
CBNumber:
CB93361772
Molecular Formula:
C21H16F4N4O3
Molecular Weight:
448.37
MOL File:
1242137-18-3.mol
Modify Date:
2023/9/12 19:13:56

Oxo Enzalutamide Properties

Density 1.48±0.1 g/cm3(Predicted)
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 13.99±0.46(Predicted)
color White to Off-White

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS08,GHS07
Signal word  Danger
Hazard statements  H360-H302
Precautionary statements  P264-P270-P301+P312-P330-P501

Oxo Enzalutamide Chemical Properties,Uses,Production

Uses

Oxo-MDV 3100 (Oxo-enzalutamide) is an impurity of Enzalutamide (M199800), which is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. Enzalutamide has been shown to induce tumor cell apoptosis, and is used for the treatment of castration-resistant prostate cancer.

Oxo Enzalutamide Preparation Products And Raw materials

Raw materials

Preparation Products

Oxo Enzalutamide 4-[3-[4-Cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methylbenzamide Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5,5-dimethyl-2,4-dioxo-1-imidazolidinyl]-2-fluoro-N-methyl- Enzalutamide Impurity J/ Enzalutamide Oxo Impurity Enzalutamide Impurities750 Enzalutamide Impurities5 4-(3-(4-cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-2,4-dioxoimidazolidin-1-yl)-2-fluoro-N-methylbenzamide? (Enzalutamide Impurity) 1242137-18-3