GUAYEWUANINE B
![GUAYEWUANINE B Structure](StructureFile/ChemBookStructure2/GIF/CB9368110.gif)
- CAS No.
- Chemical Name:
- GUAYEWUANINE B
- Synonyms
- ISOACONITINE;YUNACONITINE;JESACONITINE;GUAYEWUANINE B
- CBNumber:
- CB9368110
- Molecular Formula:
- C35H49NO12
- Molecular Weight:
- 675.76
- MOL File:
- Mol file
GUAYEWUANINE B Chemical Properties,Uses,Production
Description
A aconite alkaloid present in Aconitum fischeri Reich, A. sachalinense, Fr.
Schmidt (Saghalien) and A. subcuneaturn, Nakai, this base is amorphous but
yields crystalline salts, e.g. the perchlorate, m.p. 230-2°C (dec.); aurich10ride,
m.p. 208-9°C (dec.) and a perbromide, m.p. 181-2°C (dec.). Boiling dilute
H2S04 causes hydrolysis with the production of acetic acid and jesanisaconine
(p-anisoylaconine) forming a crystalline hydrochloride, m.p. 209- 21 O°C (dec.).Alkaline hydrolysis gives acetic and p-anisic acids and aconine. Pyrolysis furnishes
pyrojesaconitine, obtained as the crystalline perchlorate, m.p. 171-2°C; [α]13D -
27.4° (MeOH). Oxidation with KMn04 yields acetaldehyde, indicative of an
ethylimino group. The structure of the alkaloid has been determined by con_x0002_tinuous monitoring of the pyrolysis and an examination of the products
produced.
Jesaconitine is, like all of the aconitines, highly toxic producing raspiratory
paralysis and a direct toxic action on the heart, the latter often terminating in
ventricular fibrillation.
Occurrence
A complex aconitine alkaloid, yunaconitine has been isolated from Aconitum hemsJeyanum.
References
Makoshi., Arch. Pharm., 247,243 (1909)
Majima, Suginome, Morio., Ber., 57B, 1486 (1924)
Majima, Morio.,Annalen., 476,171,194,203 (1929)
Tamura., ibid, 533,183 (1937)
Structure:
Keith, Pelletier., Chem. Commun., 993 (1967)
Keith, Pelletier., ibid, 161 (1968)
Keith, Pelletier., 1. Org. Chem., 33, 2497 (1968)
GUAYEWUANINE B Preparation Products And Raw materials
Raw materials
Preparation Products
GUAYEWUANINE B Suppliers
Supplier | Tel | Country | ProdList | Advantage | Inquiry |
---|---|---|---|---|---|
Apin Chemicals Ltd. | +44 1235 832515 | United Kingdom | 6811 | 42 | Inquiry |
Scandinavian Formulas, Inc. | 215 453 2507 | United States | 1447 | 55 | Inquiry |
Shanghai Hao Zhun Biological Technology Co., Ltd. | 15800340161 | CHINA | 6846 | 58 | Inquiry |
Shanghai Yuda Industrial Co., Ltd. | 021-64133189 13788995069 | CHINA | 6107 | 58 | Inquiry |
Shenzhen Medherb Biotecnology Co., Ltd. | +86 18924660169 | China | 46 | 50 | Inquiry |
Guangzhou Weijia Technology Co., Ltd. | 020-84224925 18300190102 | CHINA | 6748 | 58 | Inquiry |
Shanghai Weiwei Biological Technology Co., Ltd. | 021-55669583 18616258598 | CHINA | 4398 | 58 | Inquiry |
Shanghai Kelei Biotechnology Co., Ltd. | 021-57880797 18116431857 | CHINA | 6188 | 58 | Inquiry |
Shanghai Xuanya Biotechnology Co., Ltd. | 021-62457717 | CHINA | 6673 | 58 | Inquiry |
Shanghai Yuanmu Biological Technology Co., Ltd. | 021-58322859 | CHINA | 6181 | 58 | Inquiry |