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Verapamil hydrochloride

Verapamil hydrochloride Structure
CAS No.
23313-68-0
Chemical Name:
Verapamil hydrochloride
Synonyms
CALAN;ISOPTIN;Veracim;Veramex;Zolvera;Dignover;Berkatens;Cardibeltin;IPROVERATRIL;VERAPAMIL HCL
CBNumber:
CB9460012
Molecular Formula:
C27H39ClN2O4
Molecular Weight:
491.06
MOL File:
23313-68-0.mol
MSDS File:
SDS
Modify Date:
2024/5/7 14:42:03
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Verapamil hydrochloride Properties

Melting point 142 °C (dec.)(lit.)
storage temp. 0-6°C
solubility methanol: 50 mg/mL, clear, colorless
form powder
color white
BCS Class 1,2
CAS DataBase Reference 23313-68-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Hazard Codes  T,Xi
Risk Statements  23/24/25-36/37/38
Safety Statements  36/37-45-37/39-26
RIDADR  UN 2811 6.1/PG 3
WGK Germany  3
RTECS  YV8320000
F  8-10

Verapamil hydrochloride Chemical Properties,Uses,Production

Chemical Properties

White Powder

Uses

A calcium channel blocker. Antihypertensive; antianginal; antiarrhythmic (class IV)

Purification Methods

The salt is purified by dissolving it in EtOH, filtering (if insoluble particles are present) and adding Et2O, filtering the salt, washing it with Et2O and drying it in vacuo. It has the following solubilities: hexane (0.001%), CH2Cl2 (~10%), MeOH (~10%), EtOH (20%) and H2O (8.3%). It has UV max at 232 and 278nm. The free base is a viscous yellow oil b 243-246o/0.01mm (n 25D 1.5448) and is almost insoluble in H2O but soluble in organic solvents. It is a Ca channel antagonist and is a coronary vasodilator. [Ramuz Helv Chim Acta 58 2050 1975, Harvey et al. Biochem J 257 95 1989.]

Verapamil hydrochloride Preparation Products And Raw materials

Raw materials

Verapamil

Preparation Products

Verapamil hydrochloride Suppliers

Global( 148)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
Lakshmi Farmachem +91-9948795885 +91-9550886476 Telangana, India 407 58 Inquiry
PIRAMAL ENTERPRISES LTD +91-22-3802 3000/4000 New Delhi, India 45 58 Inquiry
ASSURGEN PHARMA PVT LTD 0891 2567069 New Delhi, India 8 58 Inquiry
MYLAN LABORATORIES 080 6672 8000 New Delhi, India 81 58 Inquiry
SynZeal Research Pvt Ltd +1 226-802-2078 Gujarat, India 6522 58 Inquiry
RA CHEM PHARMA LTD +91-40-4475 8595 New Delhi, India 37 58 Inquiry
PIRAMAL PHARMA LTD +91-22-3802 3000 New Delhi, India 28 58 Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
Shaanxi TNJONE Pharmaceutical Co., Ltd +8618740459177 China 1142 58 Inquiry
career henan chemical co +86-0371-86658258 +8613203830695 China 29826 58 Inquiry
Supplier Advantage
Lakshmi Farmachem 58
PIRAMAL ENTERPRISES LTD 58
ASSURGEN PHARMA PVT LTD 58
MYLAN LABORATORIES 58
SynZeal Research Pvt Ltd 58
RA CHEM PHARMA LTD 58
PIRAMAL PHARMA LTD 58
OCEAN TRADING CORPORATION 58
Shaanxi TNJONE Pharmaceutical Co., Ltd 58
career henan chemical co 58

23313-68-0(Verapamil hydrochloride)Related Search:

Venlafaxine hydrochloride (+/-)-Verapamil hydrochloride R(+)-VERAPAMIL HYDROCHLORIDE,R(+)-VERAPAMIL HYDROCHLORIDE S(-)-VERAPAMIL HYDROCHLORIDE,S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE,S(-)-VERAPAMIL HYDROCHLORIDE,S(-)-VERAPAMIL HYDROCHLORIDE HYDRATE METHOXY-(-)-VERAPAMIL HYDROCHLORIDE,METHOXY-(-)-VERAPAMIL HYDROCHLORIDE
NORVERAPAMIL HYDROCHLORIDE Verapamil Benzeneacetonitrile Valeronitrile VERAPAMIL HYDROCHLORIDE EPV(CRM STANDARD),VERAPAMIL HYDROCHLORIDE EPV(CRM STANDARD)
VERAPAMIL HYDROCHLORIDE MM(CRM STANDARD),VERAPAMIL HYDROCHLORIDE MM(CRM STANDARD) VERAPAMIL HYDROCHLORIDE IMP. L (EP): 1-(3,4-DIMETHOXYPHENYL)-2-METHYLPROPAN-1-ONE BODIPY(R) FL VERAPAMIL, HYDROCHLORIDE,BODIPY(R) FL VERAPAMIL, HYDROCHLORIDE VERAPAMIL HYDROCHLORIDE IMP. E (EP): (3,4-DIMETHOXYPHENYL)METHANOL,VERAPAMIL HYDROCHLORIDE IMP. E (EP): (3,4-DIMETHOXYPHENYL)METHANOL VERAPAMIL HYDROCHLORIDE IMP. G (EP): 3,4-DIMETHOXYBENZALDEHYDE MM(CRM STANDARD)
VERAPAMIL HYDROCHLORIDE IMP. K (EP): (2RS)-2-(3,4-DIMETHOXYPHENYL)-3-METHYLBUTYLNITRILE MM(CRM STANDARD) VERAPAMIL HYDROCHLORIDE IMP. D (EP): 3-CHLORO-N-[2-(3,4-DIMETHOXYPHENYL)ETHYL]-N-METHYLPROPYL-1-AMINE MM(CRM STANDARD) VERAPAMIL HYDROCHLORIDE [N-METHYL 3H],VERAPAMIL HYDROCHLORIDE [N-METHYL 3H]
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CALAN IPROVERATRIL (+/-)-5-[N-(3,4-DIMETHOXYPHENYLETHYL)-METHYLAMINO]-2-(3,4-DIMETHOXYPHENYL)-2-ISOPROPYLVALERONITRILE HYDROCHLORIDE 5-[N-(3,4-DIMETHOXYPHENYLETHYL)METHYLAMINO]-2-(3,4-DIMETHOXYPHENYL)-2-ISOPROPYLVALERONITRILE HYDROCHLORIDE alpha-(3-((2-(3,4-dimethoxyphenyl)ethyl)methylamino)propyl)-3,4-dimethoxy-alpha-(1-methylethyl)-benzeneacetonitrile hydrochloride ALPHA-[3-[[2-(3,4-DIMETHOXYPHENYL)ETHYL]METHYLAMINO]PROPYL]-3,4-DIMETHOXY-ALPHA-(1-METHYLETHYL)BENZENEACETONITRILE HYDROCHLORIDE 5-[(3,4-DIMETHOXYPHENETHYL)METHYLAMINO]-2-(3,4-DIMETHOXYPHENYL)-2-ISOPROPYL-VALERONITRILE HYDROCHLORIDE (+/-)-VERAPAMIL HYDROCHLORIDE VERAPAMIL HYDROCHLORIDE VERAPAMIL HCL ISOPTIN a-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-a-(1-methylethyl)-benzeneacetonitrile Hydrochloride Berkatens Cardibeltin Dignover Veracim Veramex Zolvera (±)-[3-cyano-3-(3,4-dimethoxyphenyl)hex-6-yl](5,6-dimethoxyphenethyl)methylammonium chloride dl-Verapamil hydrochloride alpha-[3-[[2-(3,4-Dimethoxyphenyl)ethyl]methylamino]propyl]-3,4-dimethoxy-alpha(1-methylethyl)benzeneacetonitrile monohydrochloride 5-((3,4-diMethoxyphenethyl)(Methyl)aMino)-2-(3,4-diMethoxyphenyl)-2-isopropylpentanenitrile hydrochloride Verapamil hydrochloride USP/EP/BP 23313-68-0 C27H38N2O4.HCl Voltage-gated Ion Channels Other Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors Ion Channels BioChemical Biochemicals and Reagents Cell Biology Cell Signaling and Neuroscience Calcium Channel Modulators Intermediates & Fine Chemicals Pharmaceuticals