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MICROCYSTIN-LR

MICROCYSTIN-LR Structure
CAS No.
101043-37-2
Chemical Name:
MICROCYSTIN-LR
Synonyms
MC-LR;Microcystin-LR solution,Cyanoginosin, Fast-death factor;C05371;MCYST-LR;akerstox;toxin-lr;microcystin-a;MICROCYSTIN-LR;CYANOGINOSIN-LR;Microcystin LR 95%
CBNumber:
CB9463679
Molecular Formula:
C49H74N10O12
Molecular Weight:
995.17
MOL File:
101043-37-2.mol
MSDS File:
SDS
Modify Date:
2023/6/8 9:01:56

MICROCYSTIN-LR Properties

Density 1.29±0.1 g/cm3(Predicted)
Flash point 11 °C
storage temp. −20°C
solubility ethanol: 1 mg/mL
pka 3.03±0.70(Predicted)
form solid film
color Off-white
Stability Stable for 1 year from date of purchase as supplied. Solutions in DMSO, methanol or ethanol may be stored at -20°C for up to 2 months.
IARC 2B (Vol. 94) 2010
EPA Substance Registry System Microcystin LR (101043-37-2)

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS06
Signal word  Danger
Hazard statements  H300+H310-H315-H317-H319-H335
Precautionary statements  P261-P262-P280-P301+P310-P302+P352+P310-P305+P351+P338
Hazard Codes  T+,T,F
Risk Statements  26/27/28-36/37/38-43-39/23/24/25-23/24/25-11
Safety Statements  26-36/37/39-45-36/37-16-7
RIDADR  UN 2811 6.1/PG 1
WGK Germany  3
RTECS  GT2810000
HS Code  30029090
Toxicity LD50 orl-rat: >5 mg/kg HETOEA 18,162,1999
NFPA 704
0
4 0

MICROCYSTIN-LR Chemical Properties,Uses,Production

Description

Microcystins are hepatotoxic cyclic heptapeptide toxins produced by cyanobacteria. They are responsible for periodic poisonings of humans and livestock drinking fresh water where the blue-green algae are endemic. Microcystin-LR is a selective inhibitor of protein phosphatase 2A (PP2A) (IC50= 0.04 nM) and will completely inhibit this enzyme without affecting PP1 when used at a concentration of 0.5 nM. The PP1 IC50 is about 1.7 nM. Microcystins are at least 10 times more potent as serine/threonine PP inhibitors than okadaic acid, another microalgal toxin also used for this purpose.

Hazard

A poison by ingestion and inhalation.

Safety Profile

A poison by ingestion, inhalation,intraperitoneal, and intravenous route. Experimentalreproductive effects. When heated to decomposition itemits toxic vapors of NOx.

MICROCYSTIN-LR Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 159)Suppliers
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Hubei Ipure Biology Co., Ltd +8613367258412 China 10326 58 Inquiry
Hefei TNJ Chemical Industry Co.,Ltd. 0551-65418684 +8618949823763 China 25363 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 United States 19973 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
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Henan Fengda Chemical Co., Ltd +86-371-86557731 +86-13613820652 China 20361 58 Inquiry
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Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aitixi Biotechnology Co., Ltd 18721763493 18721763493 China 970 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
5-l-arginine-cyanoginosinl 5-l-argininecyanoginosinla MCYST-LR 5-L-ARGININE-MICROCYSTIN LA CYANOGINOSIN-LR Cyanoginosin, Fast-death factor Cyclo[D-Ala-L-Leu-[(3S)-3-methyl-D-βAsp-]-L-Arg-[(2S,3S)-2-methyl-3-[(1E,3E,5S,6S)-3,5-dimethyl-6-methoxy-7-phenyl-1,3-heptadiene-1-yl]-βAla-]-D-γGlu-N-methyl-Dha-] 5-L-Arginine-cyanoginosin C05371 MICROCYSTIN-LR MICROCYSTIN-LR, MICROCYSTIS AERUGINOSA microcystin lr from microcystis aeruginosa microcystin-lr solution TOXIN,BLUE-GREENALGA cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-leucyl-(3S)-3-methyl-D-β-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-γ-glutamyl] akerstox microcystin-a microcystisaeruginosatoxin toxin,bluegreenalga,microcystisaeruginosa toxini(microcystisaeruginosa) toxin-lr toxint17(microcystisaeruginosa) Microcystin-LR solution 10 UG/ML IN METHANOL Microcystin LR 95% CYANOGINOSIN-LR;MC-LR Microcystin LR Solution in Methanol,10μg/mL cyclo[2,3-didehydro-N-methylalanyl-D-alanyl-L-leucyl-(3S)-3-methyl-D-β-aspartyl-L-arginyl-(2S,3S,4E,6E,8S,9S)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyl-4,6-decadienoyl-D-γ-glutamyl (5R,8S,11R,12S,15S,18S,19S,22R)-15-(3-guanidinopropyl)-8-isobutyl-18-((1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxylic acid MC-LR (5R,8S,11R,12S,15S,18S,19S,22R)-15-(3-guanidinopropyl)-8-isobutyl-18-((1E,3E,5S,6S)-6-methoxy-3,5-dimethyl-7-phenylhepta-1,3-dien-1-yl)-1,5,12,19-tetramethyl-2-methylene-3,6,9,13,16,20,25-heptaoxo-1,4,7,10,14,17,21-heptaazacyclopentacosane-11,22-dicarboxy Microcystin-LR solution,Cyanoginosin, Fast-death factor Microcystin-LR Standard Solution 101043-37-2 C49H74N10O12 Kinase/Phosphatase Biology Protein Phosphatase 1 (PP1) Serine/Threonine Phosphatase Inhibitors BioChemical Cell Biology Cell Signaling and Neuroscience Natural Products