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20-CARBOXY-LEUKOTRIENE B4

20-CARBOXY-LEUKOTRIENE B4 Structure
CAS No.
80434-82-8
Chemical Name:
20-CARBOXY-LEUKOTRIENE B4
Synonyms
20-COOH-LTB4;20-CARBOXY-LEUKOTRIENE B4;20-hydroxy-20-oxoleukotriene B4;5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID;(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid;6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)-
CBNumber:
CB9769067
Molecular Formula:
C20H30O6
Molecular Weight:
366.45
MOL File:
80434-82-8.mol
Modify Date:
2024/7/2 8:55:42
Request For Quotation

20-CARBOXY-LEUKOTRIENE B4 Properties

Boiling point 588.3±50.0 °C(Predicted)
Density 1.151±0.06 g/cm3(Predicted)
Flash point 14℃
storage temp. −20°C
solubility DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS pH 7.2: 1 mg/ml
form Liquid
pka 4.66±0.10(Predicted)
color Colorless to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS02,GHS07
Signal word  Danger
Hazard statements  H225-H315-H319-H335
Precautionary statements  P210-P261-P305+P351+P338
Hazard Codes  F,Xi
Risk Statements  11-36/37/38
Safety Statements  16-26-36
RIDADR  UN 1170 3/PG 2
WGK Germany  3
NFPA 704
3
0 0

20-CARBOXY-LEUKOTRIENE B4 price More Price(1)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich(India) C6046 20-Carboxy-leukotriene B4 ~1?mg/mL in ethanol, ≥90% (HPLC) 80434-82-8 25μG ₹33290 2022-06-14 Buy
Product number Packaging Price Buy
C6046 25μG ₹33290 Buy

20-CARBOXY-LEUKOTRIENE B4 Chemical Properties,Uses,Production

Description

20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. In human leukocytes, LTB4 is inactivated by the enzyme LTB4 20-hydroxylase. The resulting 20-hydroxy LTB4 is further oxidized to 20-carboxy LTB4. LTB4 metabolism in isolated rat hepatocytes also results in production of 20-carboxy LTB4 along with other ω-oxidation products. The biological activity of 20-carboxy LTB4 is only about 2.6% compared to that of LTB4 in causing PMNL degranulation.

Uses

20-COOH-LTB4 is a leukotriene B4 metabolite and substrate for β-oxidation pathways.

Definition

ChEBI: A member of the class of leukotrienes that is leukotriene B4 in which the terminal methyl group has undergone formal oxidation to the corresponding carboxylic acid.

20-CARBOXY-LEUKOTRIENE B4 Preparation Products And Raw materials

Raw materials

Preparation Products

20-CARBOXY-LEUKOTRIENE B4 Suppliers

Global( 25)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
BIOMOL INTERNATIONAL, LP (800) 942-0430 United States 1503 77 Inquiry
Biomol Feinchemikalien GmbH 49-40-8532600 Germany 479 74 Inquiry
Interchim S.A. (33) 4 70 03 88 55 France 6307 76 Inquiry
Tebu-bio France 251 75 Inquiry
3B Scientific Corporation 847.281.9822 United States 6744 47 Inquiry
CARBONE SCIENTIFIC CO.,LTD +44(0)870 486 8629 United Kingdom 6682 30 Inquiry
SIGMA-RBI 800 736 3690 (Orders) Switzerland 6913 91 Inquiry
Riedel-de Haen AG 800 558-9160 United States 6825 87 Inquiry
Shanghai Hao Zhun Biological Technology Co., Ltd. 15800340161 CHINA 6846 58 Inquiry
Resenbio 029-86354885 China 1777 50 Inquiry
Supplier Advantage
BIOMOL INTERNATIONAL, LP 77
Biomol Feinchemikalien GmbH 74
Interchim S.A. 76
Tebu-bio 75
3B Scientific Corporation 47
CARBONE SCIENTIFIC CO.,LTD 30
SIGMA-RBI 91
Riedel-de Haen AG 87
Shanghai Hao Zhun Biological Technology Co., Ltd. 58
Resenbio 50

80434-82-8(20-CARBOXY-LEUKOTRIENE B4)Related Search:

(5S,12R)-5,12,20-TRIHYDROXY-(6Z,8E,10E,14Z)-EICOSATETRAENOIC ACID LEUKOTRIENE B4 20-CARBOXY-LEUKOTRIENE B4
20-CARBOXY-LEUKOTRIENE B4 20-COOH-LTB4 5S,12R-DIHYDROXY-6Z,8E,10E,14Z-EICOSATETRAENE-1,20-DIOIC ACID (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenedioic acid 20-hydroxy-20-oxoleukotriene B4 6,8,10,14-Eicosatetraenedioic acid, 5,12-dihydroxy-, (5S,6Z,8E,10E,12R,14Z)- 80434-82-8 C20H30O6 Lipids Fatty Acids Biochemicals and Reagents BioChemical Leukotrienes Fatty Acids Leukotrienes Lipids