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1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Structure
CAS No.
869497-75-6
Chemical Name:
1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
Synonyms
VUF 6002;VUF6002 maleate;VUF 6002 maleate;JNJ 10191584 MALEATE;JNJ 10191584 maleate salt;JNJ 10191584 maleate (VUF 6002);1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE
CBNumber:
CB9844434
Molecular Formula:
C17H19ClN4O5
Molecular Weight:
394.80956
MOL File:
869497-75-6.mol
Modify Date:
2023/9/4 15:51:00
Request For Quotation

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Properties

storage temp. Desiccate at RT
solubility DMSO: ≥10mg/mL
form powder
color off-white to light tan

SAFETY

Risk and Safety Statements

Symbol(GHS) 
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P280a-P304+P340-P405-P501a
Hazard Codes  Xn
Risk Statements  22-36/37/38
Safety Statements  26
WGK Germany  3

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Chemical Properties,Uses,Production

Uses

A highly selective histamine H4 receptor silent antagonist

Biological Activity

Highly selective histamine H 4 receptor silent antagonist; binds with high affinity to the human H 4 receptor (K i = 26 nM) and is > 540-fold selective over the H 3 receptor (K i = 14.1 μ M). In vitro, inhibits mast cell and eosinophil chemotaxis with IC 50 values of 138 and 530 nM respectively. Orally active in vivo .

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Suppliers

Global( 28)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
ATK CHEMICAL COMPANY LIMITED +undefined-21-51877795 China 32760 60 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Zhejiang J&C Biological Technology Co.,Limited +1-2135480471 +1-2135480471 China 10522 58 Inquiry
Wuhan Topule Biopharmaceutical Co., Ltd +8618327326525 China 8474 58 Inquiry
Aladdin Scientific +1-+1(833)-552-7181 United States 57511 58 Inquiry
Shanghai Aladdin Biochemical Technology Co.,Ltd. +86-18521732826 China 48467 58 Inquiry
https://hanhongsci.com/ 021-54306202 18917919676 China 29990 58 Inquiry
Nanjing Tengyi Biotechnology Co., Ltd 025-58851786 17714337195 China 5595 58 Inquiry
Aikon International Limited 18626450290 China 10718 58 Inquiry
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 China 9874 58 Inquiry
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 60
TargetMol Chemicals Inc. 58
Zhejiang J&C Biological Technology Co.,Limited 58
Wuhan Topule Biopharmaceutical Co., Ltd 58
Aladdin Scientific 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
https://hanhongsci.com/ 58
Nanjing Tengyi Biotechnology Co., Ltd 58
Aikon International Limited 58
Shanghai Chaolan Chemical Technology Center 58

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE Spectrum

1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE(869497-75-6)1HNMR

869497-75-6(1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE)Related Search:

(6-CHLORO-1H-BENZOIMIDAZOL-2-YL)-(4-METHYL-PIPERAZIN-1-YL)-METHANONE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE 1H-BENZIMIDAZOLE-2-CARBOXALDEHYDE, 5-CHLORO-
JNJ 10191584 MALEATE 1-[(5-CHLORO-1H-BENZIMIDAZOL-2-YL)CARBONYL]-4-METHYLPIPERAZINE MALEATE VUF 6002 JNJ 10191584 maleate salt VUF 6002 maleate VUF6002 maleate JNJ 10191584 maleate (VUF 6002) 869497-75-6 C13H15ClN4OC4H4O4 Other Enzyme Inhibitors and Activators. Histamine Other enzyme inhibitors and activators Histamine receptor