4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT

CAS No.: 153436-22-7

Chemical Name:: 4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT

Synonyms: GAVESTINEL;1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-;4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT;4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt

CBNumber:: CB9845365

Molecular Formula:: C18H12Cl2N2O3

Molecular Weight:: 375.21

MOL File:: 153436-22-7.mol

Modify Date:: 2023/5/4 17:34:34

Request For Quotation

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Properties

Melting point	>270°C (dec.)
Boiling point	701.1±60.0 °C(Predicted)
Density	1.561±0.06 g/cm3(Predicted)
storage temp.	Desiccate at RT
solubility	DMSO (Slightly), Methanol (Slightly)
pka	3.77±0.30(Predicted)
form	Solid
color	Pale Yellow
Stability	Hygroscopic

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Chemical Properties,Uses,Production

Uses

Treatment of stroke (N-methylD-aspartate NMDA receptor antagonist).

Biological Activity

Highly potent and selective non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (K d = 0.8 nM). Displays > 1000-fold selectivity over NMDA, AMPA and kainate binding sites. Orally bioavailable and active in vivo .

Safety Profile

A poison by intravenous route. When heated to decomposition it emits toxic vapors of NOx and Cl-.

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT Suppliers

Global( 8)Suppliers

Supplier	Tel	Country	ProdList	Advantage	Inquiry
Service Chemical Inc.	888-895-6920	Germany	6373	71	Inquiry
3B Scientific Corporation	847.281.9822	United States	6744	47	Inquiry
Lanospharma Laboratories Co.,Ltd	13440048448	China	6343	56	Inquiry
Tocris Bioscience	+44 (0) 117 916 3333	United Kingdom	5729	77	Inquiry
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	China	15848	69	Inquiry
United States Biological	800.520.3011 or 781.639.5092	United States	6256	80	Inquiry
Suzhou Chenrui Biotechnology Co. LTD	17625585511	China	520	58	Inquiry

Supplier	Advantage
Service Chemical Inc.	71
3B Scientific Corporation	47
Lanospharma Laboratories Co.,Ltd	56
Tocris Bioscience	77
3B Pharmachem (Wuhan) International Co.,Ltd.	69
United States Biological	80
Suzhou Chenrui Biotechnology Co. LTD	58

153436-22-7(4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT)Related Search:

4-CHLORO-1H-INDOLE-2-CARBALDEHYDE 6-CHLORO-2-METHYLINDOLE 6-CHLORO-1H-INDOLE-2-CARBALDEHYDE 4-chloro-1H-indole-2-carboxylic acid 6-Chloroindole-2-carboxylic acid

4,6-DICHLORO-2-METHYLINDOLE 4-CHLORO-2-METHYL-1H-INDOLE (6-CHLORO-1H-INDOL-2-YL)-METHANOL 4,6-Dichloro-1H-indole-2-carboxylic acid 4,6-Dichloro-1H-indole

4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT

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GAVESTINEL 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl)-1-propenyl]-1H-indole-2-carboxylic acid sodium salt 4,6-DICHLORO-3-[(1E)-3-OXO-3-(PHENYLAMINO)-1-PROPENYL]-1H-INDOLE-2-CARBOXYLIC ACID SODIUM SALT 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]- 153436-22-7 C18H12Cl2N2O3 C18H11Cl2N2O3Na