glybuzole

glybuzole Structure
CAS No.
1492-02-0
Chemical Name:
glybuzole
Synonyms
RP7891;AN1324;621 YT;1395 TH;Glybzole;Gludiase;glybuzole;Glybuzolum;Desaglybuzole;Sulfamidothiodiazol
CBNumber:
CB9891948
Molecular Formula:
C12H15N3O2S2
Molecular Weight:
297.401
MOL File:
1492-02-0.mol
Modify Date:
2023/5/4 17:34:33

glybuzole Properties

Melting point 163°
Boiling point 449.4±28.0 °C(Predicted)
Density 1.3286 (rough estimate)
refractive index 1.6560 (estimate)
pka 6.49±0.40(Predicted)

glybuzole Chemical Properties,Uses,Production

Originator

Gludease,Kyowa Hakko,Japan,1972

Manufacturing Process

15.7 g of 2-amino-5-tert-butyl-1,3,4-thiadiazole (0.1 mol) and 17.6 g of benzene sulfonyl chloride (0.1 mol) were dissolved in 150 ml dry pyridine and heated over steam for 4 hr. The pyridine was removed by distillation under reduced pressure and the residue treated with 50 ml 2N HCl. The solid product, MP 162° to 163°C. was filtered off and recrystallized once from benzene and twice from 50% aqueous EtOH.

Therapeutic Function

Oral hypoglycemic

glybuzole Preparation Products And Raw materials

Raw materials

Preparation Products

glybuzole Suppliers

Global( 6)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
CHEMICAL LAND21 82- 2 -783 - 8063 South Korea 6315 74 Inquiry
Service Chemical Inc. 888-895-6920 Germany 6373 71 Inquiry
Lanospharma Laboratories Co.,Ltd 13440048448 China 6343 56 Inquiry
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd 15229059051 China 9976 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 23962 58 Inquiry
BENZENESULPHONAMIDE,N-(5-TERT-BUTYL-1,3,4-THIADIAZOL-2-YL)- 1395 TH 621 YT AN1324 Gludiase Glybzole RP7891 N-(5-tert-butyl-1,3,4-thiadiazol-2-yl)benzenesulfonamide glybuzole Desaglybuzole Glybuzolum Sulfamidothiodiazol Benzenesulfonamide, N-[5-(1,1-dimethylethyl)-1,3,4-thiadiazol-2-yl]- 1492-02-0