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(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate

(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate Structure
CAS No.
30392-41-7
Chemical Name:
(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate
Synonyms
Bitol;S-1540;Biterol;Effectin;Win-32784;Tornalate;Bitolterol Mesylate;Bitoterol Methanesulfonate;(tert-butyl)[β-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate;(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate
CBNumber:
CB9932153
Molecular Formula:
C45H64N2O5S
Molecular Weight:
745.06506
MOL File:
30392-41-7.mol
MSDS File:
SDS
Modify Date:
2023/4/23 13:52:06

(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate Properties

Melting point 170-172°
storage temp. Refrigerator
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color Off-White to Light Beige

(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate Chemical Properties,Uses,Production

Description

Bitolterol is a prodrug that releases colterol on activation by esterases in the lung. Colterol is a direct-acting agonist, and the N-t-butyl group makes it β2-selective with a binding potency equivalent to that of isoetharine and terbutaline. The ester form is lipophilic, which helps to keep it local in the lung and resistant to COMT, which tends to increase its duration of action. Onset begins 2 to 4 minutes after administration, and the effect can last as long as 8 hours. It has a adverse effect profile similar to that of other β2-selective agonists, with less drowsiness and restlessness compared to other direct-acting agonists.

Uses

β2-adrenergic receptor agonist

Definition

ChEBI: The methanesulfonate salt of bitolterol. A beta2-adrenergic receptor agonist, it is used for relief of bronchospasm in conditions such as asthma, chronic bronchitis and emphysema.

(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate Preparation Products And Raw materials

Raw materials

Preparation Products

(tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate Suppliers

Global( 15)Suppliers
Supplier Tel Country ProdList Advantage Inquiry
OCEAN TRADING CORPORATION +91(22) 24921669 New Delhi, India 6211 58 Inquiry
CLEARSYNTH LABS LTD. +91-22-45045900 Hyderabad, India 6351 58 Inquiry
Pharmaffiliates Analytics and Synthetics P. Ltd +91-172-5066494 Haryana, India 6773 58 Inquiry
Pharma Affiliates 172-5066494 Haryana, India 6761 58 Inquiry
TargetMol Chemicals Inc. +1-781-999-5354 +1-00000000000 United States 19892 58 Inquiry
Dideu Industries Group Limited +86-29-89586680 +86-15129568250 China 25298 58 Inquiry
TargetMol Chemicals Inc. 4008200310 China 24017 58 Inquiry
Waterstone Technology, LLC 317 644 0862 United States 6801 30 Inquiry
CarboMer, Inc. 858 552 0992 United States 4027 67 Inquiry
Carbosynth +86 512 6260 5585 United Kingdom 6018 58 Inquiry
Bitol Effectin S-1540 Tornalate Win-32784 Biterol Bitoterol Methanesulfonate (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate Bitolterol Mesylate (tert-butyl)[β-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate (tert-butyl)[beta-hydroxy-3,4-bis(p-toluoyloxy)phenethyl]ammonium methanesulphonate USP/EP/BP 30392-41-7 C29H35NO8S