Amphomycin

Amphomycin Structure
CAS No.
1402-82-0
Chemical Name:
Amphomycin
Synonyms
amfamycin;Nsc267431;Amphomycin
CBNumber:
CB9938498
Molecular Formula:
C58H91N13O20
Molecular Weight:
1290.43
MOL File:
1402-82-0.mol
MSDS File:
SDS
Modify Date:
2023/5/21 10:59:17

Amphomycin Properties

alpha D25 +7.5° (c = 1 at pH 6)
Boiling point 854.06°C (rough estimate)
Density 1.0985 (rough estimate)
refractive index 1.6700 (estimate)
storage temp. Store at -20°C
solubility Soluble in DMSO
form solid
color Crystals

SAFETY

Risk and Safety Statements

Toxicity LD50 orl-mus: 500 mg/kg 85GDA2 4(1),317,80

Amphomycin Chemical Properties,Uses,Production

Uses

Amphomycin is a lipopeptide antibiotic produced by Streptomycetes and Actinoplanes, initially reported by researchers at Bristol-Myers in 1953 from Streptomyces canus. Amphomycin was marketed as a complex of closely related analogues in the 1950s and 1960s. Structure elucidation was not completed until 2000. Amphomycin is active against Gram positive bacteria, inhibiting peptidoglycan synthesis and blocking cell wall development. Amphomycin is closely related to a number of “lost” antibiotics, aspartocin, crystallomycin, glumamycin, friulimicin, laspartocin, tsushimycin and zaomycin. Interest in amphomycin was re-awakened with the discovery of friulimicin activity against antibiotic resistant strains.

Safety Profile

Poison by intravenous andintraperitoneal routes. Moderately toxic by ingestion.Induces hemolysis. Active against gram-positive bacteria.Suggested as a topical agent for animal and plantinfections. When heated to decomposition it emits acridsmoke and

Amphomycin Preparation Products And Raw materials

Raw materials

Preparation Products

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Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 China 8739 58 Inquiry
Amphomycin Nsc267431 amfamycin 1402-82-0 C58H91N13O20