LY 311727

LY 311727 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
Sigma-Aldrich Japan	L6795	LY 311727 ≥98% (HPLC), powder LY311727 ≥98% (HPLC), powder	164083-84-5	25mg	￥104800	2021-03-23	購入
Sigma-Aldrich Japan	L6795	LY 311727 ≥98% (HPLC), powder LY311727 ≥98% (HPLC), powder	164083-84-5	5mg	￥32100	2018-12-25	購入

LY 311727 化学特性,用途語,生産方法

説明

Secreted phospholipase A₂ (sPLA₂) isoforms are low molecular weight, millimolar calcium-dependent enzymes that hydrolyze the fatty acid from the sn-2 position of membrane phospholipids. Group IIA sPLA₂, also known as sPLA₂IIA and non-pancreatic sPLA₂, has roles in the regulation of eicosanoid synthesis and may modulate inflammatory signaling. LY311727 is an inhibitor of Group IIA sPLA₂ (IC₅₀ = 0.47 μM) that interacts with the active site of the enzyme in a non-covalent manner. It shows greater than 1,500-fold selectivity over pancreatic sPLA₂ (Group IB sPLA₂). LY311727 is commonly used to distinguish the actions of Group IIA sPLA₂ from those of other sPLA₂ isoforms in biological systems.

使用

LY311727 is an inhibitor of Group IIA sPLA2 (IC50 = 0.47 μM) that interacts with the active site of the enzyme in a non-covalent manner. It shows greater than 1,500-fold selectivity over pancreatic sPLA2 (Group IB sPLA2). LY311727 is commonly used to distinguish the actions of Group IIA sPLA2 from those of other sPLA2 isoforms in biological systems.[Cayman Chemical]

Biochem/physiol Actions

LY311727 is an orally active; potent secretory Phospholipase A2 (sPLA2; Group IIa) inhibitor.

LY 311727 上流と下流の製品情報

原材料

準備製品

LY 311727 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Nanjing Qishi Biotechnology Co. Ltd.	19822610310	3122922726@qq.com	China	1346	58
BOC Sciences	--	info@bocsci.com	USA	0	65
DC Chemicals	021-58447131 13564518121	sales@dcchemicals.com	China	9412	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58

164083-84-5(LY 311727)キーワード:

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• 164083-84-5
• [3-[[3-(2-Amino-2-oxoethyl)-2-ethyl-1-(phenylmethyl)-1H-indol-5-yl]oxy]propyl]-phosphonicacid
• LY 311727
• Phosphonic acid, P-[3-[[3-(2-aMino-2-oxoethyl)-2-ethyl-1-(phenylMethyl)-1H-indol-5-yl]oxy]propyl]-
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• 3-(1-Benzyl-2-ethyl-3-carboxamido-methyl-indol-5-yl)-oxy-propan-ephosphonic acid
• LY 311727
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• LY-311727
• (3-{[1-ベンジル-3-(カルバモイルメチル)-2-エチル-1H-インドール-5-イル]オキシ}プロピル)ホスホン酸
• 3-[[3-(2-アミノ-2-オキソエチル)-2-エチル-1-ベンジル-1H-インドール-5-イル]オキシ]プロピルホスホン酸