Boc-NH-PEG2-CH2COOH
Boc-NH-PEG2-CH2COOH 物理性質
- 沸点 :
- 425.7±30.0 °C(Predicted)
- 比重(密度) :
- 1.145±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- -20°C
- 酸解離定数(Pka):
- 3.40±0.10(Predicted)
- 外見 :
- liquid
- 色:
- Yellow
- InChI:
- InChI=1S/C11H21NO6/c1-11(2,3)18-10(15)12-4-5-16-6-7-17-8-9(13)14/h4-8H2,1-3H3,(H,12,15)(H,13,14)
- InChIKey:
- OMBVJVWVXRNDSL-UHFFFAOYSA-N
- SMILES:
- C(O)(=O)COCCOCCNC(=O)OC(C)(C)C
Boc-NH-PEG2-CH2COOH 価格
もっと(9)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-9563 |
Boc-8-amino-3,6-dioxaoctanoic acid |
108466-89-3 |
1g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-9563 |
Boc-8-amino-3,6-dioxaoctanoic acid |
108466-89-3 |
250mg |
￥41400 |
2020-09-21 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-9563 |
Boc-8-amino-3,6-dioxaoctanoic acid |
108466-89-3 |
5g |
￥17000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-9563 |
Boc-8-amino-3,6-dioxaoctanoic acid |
108466-89-3 |
10g |
￥30000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBQC-9563 |
Boc-8-amino-3,6-dioxaoctanoic acid |
108466-89-3 |
25g |
￥70000 |
2024-03-01 |
購入 |
Boc-NH-PEG2-CH2COOH 化学特性,用途語,生産方法
使用
t-Boc-
N-amido-PEG
2-CH
2CO
2H is a heterobifunctional, PEGylated crosslinker featuring a Boc-protected amine at one end and a carboxyl group at the other. The hydrophillic PEG linker facilitates solubility in biological applications. t-Boc-
N-amido-PEG
2-CH
2CO
2H can be used for bioconjugation or as a building block for synthesis of small molecules, conjugates of small molecules and/or biomolecules, or other tool compounds for chemical biology and medicinal chemistry that require ligation. Examples of applications include its synthetic incorporation into antibody-drug conjugates or proteolysis-targeting chimeras (PROTAC
? molecules) for
targeted protein degradation.
合成
To a stirred solution of 2-(2-(2-Aminoethoxy)ethoxy)acetic acid (5.0 g, 30.6 mmol) in 1,4-Dioxane (50 mL), Sodium carbonate (8.12 g, 76.5 mmol, dissolved in 10 mL water) and (Boc)2O (9.98 mL, 45.7 mmol) were added and stirred at room temperature for 12 h. The progress of the reaction was monitored by TLC. The reaction mass was partitioned between diethyl ether and water. Then, the aqueous layer was made acidic (pH = 3) by 3N HC1 solution and was extracted with DCM (2 x 200 mL). The organic layer was washed with water, and brine, dried over Na2504 and evaporated under reduced pressure to yield 50 g of pure Boc-NH-PEG2-CH2COOH (Yield:62.1 per cent).
Boc-NH-PEG2-CH2COOH 上流と下流の製品情報
原材料
準備製品
Boc-NH-PEG2-CH2COOH 生産企業
Global( 164)Suppliers
108466-89-3()キーワード:
1-BOC-アミノ-3,6,9-トリオキサウンデカニル-11-オール
13-アミノ-5,8,11-トリオキサ-2-アザトリデカン酸1,1-ジメチルエチルエステル
T-BOC-N-AMIDO-DPEG®₁₂-ACID
N-(tert-ブトキシカルボニル)-2-(2-アミノエトキシ)エチルアミン
21-[(tert-ブトキシカルボニル)アミノ]-4,7,10,13,16,19-ヘキサオキサヘンエイコサン酸
(Boc-アミノ)-PEG4-カルボン酸
(Boc-アミノ)-PEG3-C2-カルボン酸
O-(2-アミノエチル)-O'-[2-(BOC-アミノ)エチル]ヘキサエチレングリコール
3-[2-(2-([(TERT-ブチルトキシ)カルボニル]アミノ)エトキシ)エトキシ]プロパン酸
2,2-ジメチル-4-オキソ-3,8,11,14-テトラオキサ-5-アザヘキサデカン-16-酸
- 108466-89-3
- Boc-N-amido-PEG2-CH2CO2H
- t-boc-N-amido-PEG2-acetic acid
- 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo-
- 8-tert-butyloxycarbonylaMino-3,6-dioxaoctanoic acid
- t-Boc-N-amido-PEG2-CH2CO2H
- BocNH-PEG2-CH2COOH
- T-BOC-NH-AMIDO-PEG2-CH2CO2H
- 2-[2-[2-(Boc-amino)ethoxy]ethoxy]acetic Acid
- 2-[2-(2-{[(tert-butoxy)carbonyl]amino}ethoxy)ethoxy]acetic acid
- 3,6,11-Trioxa-9-azatridecanoic acid, 12,12-dimethyl-10-oxo-
- 3,8,11-Trioxa-5-azatridecan-13-oic acid, 2,2-diMethyl-4-oxo- USP/EP/BP
- 11-Trioxa-5-azatridecan-13-oic acid
- 2-diMethyl-4-oxo-
- 2,2-DiMethyl-4-oxo-3,8,11-trioxa-5-azatridecan-13-oic acid
- 2-[2-[2-[(2-Methylpropan-2-yl)oxycarbonylaMino]ethoxy]ethoxy]acetic acid
- Boc-AEEA-OH
- NHBoc-PEG2-CH2COOH
- t-Boc-N-Amido-PEG2-CH2COOH
- N-Boc-8-amino-3,6-dioxaoctanoic acid
- Boc-O 2 Oc-OH
- 2-[2-(2-([(tert-butoxy)carbonylaminoJethoxy)ethoxylacetic acid
- 2,2-dimethyl-4,13-dioxo-3,8,11-trioxa-5-azatetradecan-14-oic acid