Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

168958-19-8

CAS番号.: 168958-19-8

化学名:

别名:

英語名:: Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

英語别名:: Peramivir Impurity 37;(1R,4R)-methyl 4-(tert-butoxycarbonylamino)cyclopent-2-enecarboxylate;Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester;2-Cyclopentene-1-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,4R)-

CBNumber:: CB02729183

化学式:: C12H19NO4

分子量:: 241.28

MOL File:: 168958-19-8.mol

物理性質

安全性情報

用途語

生産企業 23

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester 物理性質

沸点 :: 331.2±42.0 °C(Predicted)

比重(密度) :: 1.10±0.1 g/cm3(Predicted)

溶解性:: soluble in Methanol

酸解離定数(Pka):: 11.75±0.40(Predicted)

安全性情報

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester 化学特性,用途語,生産方法

使用

(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester 上流と下流の製品情報

原材料

準備製品

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester 生産企業

Global( 23)Suppliers

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Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4022	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+8618627948422	sale@hdimpurity.com	China	3389	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18021	56
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Hubei Yangxin Medical Technology Co., Ltd.	15374522761	3003392093@qq.com	China	8345	55
Xenoah Pharmaceutical Inc.	0512-6956-1983	info@xenoah.com	China	296	58
Yangzhou Changhua Biotechnology Co., Ltd.	13815846020; 13815846020	438399391@qq.com	China	857	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1081	58

168958-19-8()キーワード:

(1R,4S)-4-アミノシクロペント-2-エン-1-カルボン酸メチル塩酸塩 4-((TERT-ブチルトキシカルボニル)アミノ)シクロペント-2-エンカルボン酸(1S,4R)-メチル (3AR,4R,6S,6AS)-4-[[(1,1-ジメチルエトキシ)カルボニル]アミノ]-3-(1-エチルプロピル)-3A,5,6,6A-テトラヒドロ-4H-シクロペント[D]イソオキサゾール-6-カルボン酸メチルエステル

168958-19-8
Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
(1R,4R)-methyl 4-(tert-butoxycarbonylamino)cyclopent-2-enecarboxylate
Peramivir Impurity 37
2-Cyclopentene-1-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,4R)-