Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

168958-19-8

CAS-Nr.: 168958-19-8

Englisch Name:: Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester

Synonyma:: Peramivir Impurity 37;(1R,4R)-methyl 4-(tert-butoxycarbonylamino)cyclopent-2-enecarboxylate;Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester;2-Cyclopentene-1-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,4R)-

CBNumber:: CB02729183

Summenformel:: C12H19NO4

Molgewicht:: 241.28

MOL-Datei:: 168958-19-8.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 23

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Eigenschaften

Siedepunkt:: 331.2±42.0 °C(Predicted)

Dichte: 1.10±0.1 g/cm3(Predicted)

Löslichkeit: soluble in Methanol

pka: 11.75±0.40(Predicted)

Sicherheit

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

(1R,4R)-4-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-cyclopentene-1-carboxylic Acid Methyl Ester is an intermediate in synthesizing trans-Abacavir Dihydrochloride (A104995), which is an impurity of Abacavir. Abacavir (A104990) is a carbocyclic 2''-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection (1). Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA (2). Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 23)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shanxi Xuanran Import and Export Trade Co., Ltd.	+8617735180244	mike_yan@xuanranglobal.com	CHINA	4022	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58
China National Standard Pharmaceutical Corporation Limited	+8615391658522	overseasales@yongstandards.com	China	11927	58
ShenZhen H&D Pharmaceutical Technology Co., LTD	+86-0755-22677845 +86-13627253706	sale@hdimpurity.com	China	2903	58
ChemStrong Scientific Co.,Ltd	0755-0755-66853366 13670046396	sales@chem-strong.com	China	18018	56
Shanghai Kewel Chemical Co., Ltd.	021-64609169 18901607656	greensnown@163.com	China	9911	50
Hubei Yangxin Medical Technology Co., Ltd.	15374522761	3003392093@qq.com	China	8046	55
Xenoah Pharmaceutical Inc.	0512-6956-1983	info@xenoah.com	China	296	58
Yangzhou Changhua Biotechnology Co., Ltd.	13815846020; 13815846020	438399391@qq.com	China	851	58
Guangzhou Jiuzhi Pharmaceutical Technology Co., Ltd.	020-89854820	sales@jzpharma.cn	China	1050	58

Trans-(1R,4R)-4-Boc-aMino-2-Cyclopentene-1-carboxylic acid Methyl ester
(1R,4R)-methyl 4-(tert-butoxycarbonylamino)cyclopent-2-enecarboxylate
Peramivir Impurity 37
2-Cyclopentene-1-carboxylic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-, methyl ester, (1R,4R)-
168958-19-8