Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate

 化学構造式
112889-02-8
CAS番号.
112889-02-8
化学名:
别名:
英語名:
Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate
英語别名:
Raltitrexed Impurity 24;diethyl n-[5-methylamino-2-thenoyl]-l-glutamate;Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP;(S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate;n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester;iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate;L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
CBNumber:
CB0855299
化学式:
C15H22N2O5S
分子量:
342.41
MOL File:
112889-02-8.mol

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 物理性質

沸点 :
519.6±50.0 °C(Predicted)
比重(密度) :
1.231
貯蔵温度 :
under inert gas (nitrogen or Argon) at 2–8 °C
酸解離定数(Pka):
12.89±0.46(Predicted)

安全性情報

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01FLC435309
(S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate
112889-02-8 250mg ¥15600 2021-03-23 購入
富士フイルム和光純薬株式会社(wako) W01FLC435309
(S)-Diethyl 2-(5-(methylamino)thiophene-2-carboxamido)pentanedioate
112889-02-8 1g ¥38100 2021-03-23 購入

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 化学特性,用途語,生産方法

使用

N-[[5-(Methylamino)-2-thienyl]carbonyl]-L-glutamic Acid Diethyl Ester can be used as reactant/reagent for synthetic preparation of Raltitrexed (anticancer agent). An intermediate or impurity in the synthesis of Raltitrexed (R100500). Raltitrexed (R100500) is folate-based inhibitor of thymidylate synthase; rapidly and extensively metabolized to its more potent polyglutamate derivatives. Antineoplastic.

Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 上流と下流の製品情報

原材料

準備製品


Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate 生産企業

Global( 66)Suppliers
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112889-02-8()キーワード:


  • 112889-02-8
  • n-[[5-(methylamino)-2-thienyl]carbonyl]-l-glutamic acid diethyl ester
  • diethyl n-[5-methylamino-2-thenoyl]-l-glutamate
  • (S)-Diethyl 2-(5-(MethylaMino)thiophene-2-carboxaMido)pentanedioate
  • L-Glutamic acid, N-[[5-(methylamino)-2-thienyl]carbonyl]-, 1,5-diethyl ester
  • iethyl(2S)-2-[[5-(methylamino)thiophene-2-carbonyl]amino]pentanedioate
  • Diethyl N-[5-methylamino-2-thenoyl]-L-glutamate USP/EP/BP
  • Raltitrexed Impurity 24
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