補体因子D ヒト血漿由来

補体因子D ヒト血漿由来 化学構造式
37213-56-2
CAS番号.
37213-56-2
化学名:
補体因子D ヒト血漿由来
别名:
補体因子D ヒト血漿由来
英語名:
FACTOR D, HUMAN
英語别名:
ADIPSIN;ADIPSIN, HUMAN;FACTOR D, HUMAN;COMPLEMENT FACTOR D;C3 ACTIVATOR CONVERTASE;C3 ACTIVATOR CONVERTASE, HUMAN;complement factor D from human plasma
CBNumber:
CB1172960
化学式:
分子量:
0
MOL File:
Mol file

補体因子D ヒト血漿由来 物理性質

貯蔵温度 :
−70°C

安全性情報

主な危険性  B
WGK Germany  3

補体因子D ヒト血漿由来 価格 もっと(3)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
Sigma-Aldrich Japan C5688 補体因子D ヒト血漿由来 90-110?μg/mL in PBS, pH 7.2, ≥90% (SDS-PAGE)
Complement factor D from human plasma 90-110?μg/mL in PBS, pH 7.2, ≥90% (SDS-PAGE)
37213-56-2 10μg ¥56500 2024-03-01 購入
Sigma-Aldrich Japan 341273 Factor D, Human, is a native single-chain glycoprotein with serine protease activity. Cleaves, and thus activates, Factor B during activation of complement via the alternative pathway.
Factor D, Human Factor D, Human, is a native single-chain glycoprotein with serine protease activity. Cleaves, and thus activates, Factor B during activation of complement via the alternative pathway.
37213-56-2 25μG ¥73800 2024-03-01 購入
Sigma-Aldrich Japan C5688 補体因子D ヒト血漿由来 90-110?μg/mL in PBS, pH 7.2, ≥90% (SDS-PAGE)
Complement factor D from human plasma 90-110?μg/mL in PBS, pH 7.2, ≥90% (SDS-PAGE)
37213-56-2 10ug ¥68100 2018-12-25 購入

補体因子D ヒト血漿由来 化学特性,用途語,生産方法

使用

Complement factor D is a serine protease essential for the activation of the alternative pathway in the complement system. Research of complement factor D has revealed that a self inhibitory loop is responsible for switch from a resting to active state. Additionally, recent research has linked a complement factor D gene, single nucleotide polymorphism (SNP) rs3826945, with age-related macular degeneration (AMD). In these AMD cases there was a significant increase in plasma complement factor D concentration, even though previous research has shown no association between complement factor D SNP genes and AMD.

Biochem/physiol Actions

Complement factor D is a serine protease with structural homologies with chymotrypsin. In the complement cascade, factor D cleaves complement factor B in complex with activated complement component C3. It is identical to adipsin, which is expressed in adipose tissue.

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