FACTOR D, HUMAN
- CAS No.
- 37213-56-2
- Chemical Name:
- FACTOR D, HUMAN
- Synonyms
- ADIPSIN;ADIPSIN, HUMAN;FACTOR D, HUMAN;COMPLEMENT FACTOR D;C3 ACTIVATOR CONVERTASE;C3 ACTIVATOR CONVERTASE, HUMAN;complement factor D from human plasma
- CBNumber:
- CB1172960
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00166417
- MOL File:
- Mol file
| storage temp. | −70°C |
|---|---|
| FDA UNII | 3YX5QCW28B |
SAFETY
Risk and Safety Statements
| Hazard Codes | B |
|---|---|
| WGK Germany | 3 |
FACTOR D, HUMAN price More Price(9)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C5688 | Complement factor D from human plasma 90-110?μg/mL in PBS, pH 7.2, ≥90% (SDS-PAGE) | 37213-56-2 | 10μg | $402 | 2024-03-01 | Buy |
| Sigma-Aldrich | 341273 | Factor D, Human Factor D, Human, is a native single-chain glycoprotein with serine protease activity. Cleaves, and thus activates, Factor B during activation of complement via the alternative pathway. | 37213-56-2 | 25μg | $506 | 2024-03-01 | Buy |
| Sigma-Aldrich | 341273 | Factor D, Human | 37213-56-2 | 25ug | $373 | 2021-12-16 | Buy |
| Usbiological | 471913 | Complement Factor D | 37213-56-2 | 96Tests | $731 | 2021-12-16 | Buy |
| Usbiological | 024384 | Complement Factor D | 37213-56-2 | 96Tests | $851 | 2021-12-16 | Buy |
FACTOR D, HUMAN Chemical Properties,Uses,Production
Uses
Complement factor D is a serine protease essential for the activation of the alternative pathway in the complement system. Research of complement factor D has revealed that a self inhibitory loop is responsible for switch from a resting to active state. Additionally, recent research has linked a complement factor D gene, single nucleotide polymorphism (SNP) rs3826945, with age-related macular degeneration (AMD). In these AMD cases there was a significant increase in plasma complement factor D concentration, even though previous research has shown no association between complement factor D SNP genes and AMD.
Biochem/physiol Actions
Complement factor D is a serine protease with structural homologies with chymotrypsin. In the complement cascade, factor D cleaves complement factor B in complex with activated complement component C3. It is identical to adipsin, which is expressed in adipose tissue.
FACTOR D, HUMAN Preparation Products And Raw materials
Raw materials
Preparation Products
FACTOR D, HUMAN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| Aladdin Scientific | 58 |
| Sigma-Aldrich | 80 |
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