UCB35625 化学特性,用途語,生産方法
生物活性
Potent chemokine CCR1 and CCR3 receptor antagonist. Inhibits MIP-1 α -induced chemotaxis in CCR1 transfectants and eotaxin-induced chemotaxis in CCR3 transfectants (IC 50 values are 9.57 and 93.8 nM respectively). Antagonizes CCR3-mediated entry of HIV-1 isolate 89.6 into NP-2 cells (IC 50 = 57 nM). Isomer of J 113863 (1,4-cis-1-(1-Cycloocten-1-ylmethyl)-4-[[(2,7-dichloro-9H-xanthen-9-yl)carbonyl]amino]-1-ethylpiperidiniumiodide ).
UCB35625 上流と下流の製品情報
原材料
準備製品