(±)10(11)-EpDPA

 化学構造式
895127-65-8
CAS番号.
895127-65-8
化学名:
别名:
英語名:
(±)10(11)-EpDPA
英語别名:
(±)10(11)-EpDPA;10(11)-Epoxy-Docosapentaenoic acid;4,7-Nonadienoic acid, 9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-, (4Z,7Z)-;(4(Z),7Z)-9-[3-(2(Z),5(Z),8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid
CBNumber:
CB13152404
化学式:
C22H32O3
分子量:
344.49
MOL File:
895127-65-8.mol

(±)10(11)-EpDPA 物理性質

沸点 :
488.8±33.0 °C(Predicted)
比重(密度) :
0.994±0.06 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
DMF: 25 mg/mL; DMSO: 20 mg/mL; Ethanol: 50 mg/mL; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
酸解離定数(Pka):
4.58±0.10(Predicted)

安全性情報

(±)10(11)-EpDPA 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

(±)10(11)-EpDPA 化学特性,用途語,生産方法

説明

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA; ) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.

(±)10(11)-EpDPA 上流と下流の製品情報

原材料

準備製品


(±)10(11)-EpDPA 生産企業

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  • 895127-65-8
  • (±)10(11)-EpDPA
  • (4(Z),7Z)-9-[3-(2(Z),5(Z),8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid
  • 10(11)-Epoxy-Docosapentaenoic acid
  • 4,7-Nonadienoic acid, 9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-, (4Z,7Z)-
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