(±)10(11)-EpDPA

(±)10(11)-EpDPA Struktur
895127-65-8
CAS-Nr.
895127-65-8
Englisch Name:
(±)10(11)-EpDPA
Synonyma:
(±)10(11)-EpDPA;10(11)-Epoxy-Docosapentaenoic acid;4,7-Nonadienoic acid, 9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-, (4Z,7Z)-;(4(Z),7Z)-9-[3-(2(Z),5(Z),8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid
CBNumber:
CB13152404
Summenformel:
C22H32O3
Molgewicht:
344.49
MOL-Datei:
895127-65-8.mol

(±)10(11)-EpDPA Eigenschaften

Siedepunkt:
488.8±33.0 °C(Predicted)
Dichte
0.994±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
Löslichkeit
DMF: 25 mg/mL; DMSO: 20 mg/mL; Ethanol: 50 mg/mL; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/mL
pka
4.58±0.10(Predicted)

Sicherheit

(±)10(11)-EpDPA Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Cytochrome P450 metabolism of polyunsaturated fatty acids produces numerous bioactive epoxide regioisomers. (±)10(11)-EpDPA is a docosahexaenoic acid (DHA; ) epoxygenase metabolite, derived via epoxidation of the 10,11-double bond of DHA. It has been detected in rat brain and spinal cord, as well as human serum, and acts as a substrate for soluble epoxide hydrolase with a Km value of 5.1 μM. (±)10(11)-EpDPA and other epoxy metabolites of DHA are reported to demonstrate antihyperalgesic activity in inflammatory and neuropathic pain models and to potently inhibit angiogenesis and tumor growth in in vitro assays.

(±)10(11)-EpDPA Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


(±)10(11)-EpDPA Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • (±)10(11)-EpDPA
  • (4(Z),7Z)-9-[3-(2(Z),5(Z),8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-4,7-nonadienoic acid
  • 10(11)-Epoxy-Docosapentaenoic acid
  • 4,7-Nonadienoic acid, 9-[3-(2Z,5Z,8Z)-2,5,8-undecatrien-1-yl-2-oxiranyl]-, (4Z,7Z)-
  • 895127-65-8
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