POMALIDOMIDE-PEG1-CO2H

POMALIDOMIDE-PEG1-CO2H 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

POMALIDOMIDE-PEG1-CO2H 化学特性,用途語,生産方法

使用

Protein degrader builiding block Pomalidomide-PEG₁-CO₂H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

POMALIDOMIDE-PEG1-CO2H 上流と下流の製品情報

原材料

準備製品

POMALIDOMIDE-PEG1-CO2H 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Wuhan Borenpharm Co., Ltd	027-65563561 18717150066	3207347307@qq.com	CHINA	1238	58
CR Corporation Limited	+8613062833949	fred.wen@crcorporation.cn	China	8647	58
Zhengzhou Lingzhiyue Technology Co., Ltd	+86-0371-55074660 +86-13783527580	Lingzhiyue@aliyun.com	China	3152	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43348	58
Nanjing Bicbiotechnology Co., Ltd	+86-2552131256 +86-18251840740	sales@bicbiotech.com	China	6000	58
Jilin Chinese Academy of Sciences-yanshen Technology	+undefined18143011203	info@chemextension.com	China	42057	58
Xian confluore Biological Technology Co., Ltd.	+86-15680926068 +86-15680926068	1924344760@confluore.cn	China	2996	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57511	58
Suzhou ARTK Medchem Co., Ltd.	+8618168183658	sales1@artkmedchem.com	China	39010	58
Daicel Chiral Technologies (China)CO.,LTD	021-50460086-9 15921403865	han_yajun@dctc.daicel.com	China	7182	65

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• 2139348-60-8
• Pomalidomide-PEG1-C2-COOH
• Pomalidomide-PEG1-COOH
• Pomalidomide-PEG1-CO2H >=95%
• POMALIDOMIDE-PEG1-CO2H
• 3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid
• Thalidomide-4-NH-PEG1-COOH
• Thalidomide-NH-PEG1-C2-COOH
• Propanoic acid, 3-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]-
• 3-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid, Crosslinker–E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
• Thalidomide-4-NH-PEG1-C2-COOH
• Poma-PEG1-COOH
• Pomalidomide 4'-PEG1-acid
• 3-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]propanoic Acid
• 3-(2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}ethoxy)propanoic acid