ChemicalBook >> CAS DataBase List >>POMALIDOMIDE-PEG1-CO2H
POMALIDOMIDE-PEG1-CO2H
- CAS No.
- 2139348-60-8
- Chemical Name:
- POMALIDOMIDE-PEG1-CO2H
- Synonyms
- 3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid;Poma-PEG1-COOH;POMALIDOMIDE-PEG1-CO2H;Pomalidomide-PEG1-COOH;Pomalidomide-PEG1-C2-COOH;Pomalidomide 4'-PEG1-acid;Thalidomide-4-NH-PEG1-COOH;Thalidomide-NH-PEG1-C2-COOH;Pomalidomide-PEG1-CO2H >=95%;Thalidomide-4-NH-PEG1-C2-COOH
- CBNumber:
- CB14743861
- Molecular Formula:
- C18H19N3O7
- Molecular Weight:
- 389.36
- MDL Number:
- MFCD32063496
- MOL File:
- 2139348-60-8.mol
- MSDS File:
- SDS
Last updated:2024-07-02 08:55:01
POMALIDOMIDE-PEG1-CO2H Chemical Properties,Uses,Production
Uses
Protein degrader builiding block Pomalidomide-PEG1-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
storage
Store at -20°C
POMALIDOMIDE-PEG1-CO2H Preparation Products And Raw materials
Raw materials
Preparation Products
POMALIDOMIDE-PEG1-CO2H Suppliers
Global( 37)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
| Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3152 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 6000 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Suzhou ARTK Medchem Co., Ltd. | +8618168183658 | sales1@artkmedchem.com | China | 39009 | 58 |
| Daicel Chiral Technologies (China)CO.,LTD | 021-50460086-9 15921403865 | han_yajun@dctc.daicel.com | China | 6943 | 65 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66113011 18112977050 | cb6@aikonchem.com | China | 16687 | 50 |
View Lastest Price from POMALIDOMIDE-PEG1-CO2H manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-02 | Pomalidomide-PEG1-COOH
2139348-60-8
|
US $0.00 / mg | 250mg | >99.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
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- Pomalidomide-PEG1-COOH
2139348-60-8
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
2139348-60-8(POMALIDOMIDE-PEG1-CO2H)Related Search:
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Pomalidomide-PEG3-CO2H
POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG1-azide
Pomalidomide-O-C4-NH2
Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG3-N3
Pomalidomide-PEG6-butyl iodide
Pomalidomide-PEG5-CO2H
E3 ligase Ligand-Linker Conjugates 50
1of4
Pomalidomide-PEG1-C2-COOH
Pomalidomide-PEG1-COOH
Pomalidomide-PEG1-CO2H >=95%
POMALIDOMIDE-PEG1-CO2H
3-(2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid
Thalidomide-4-NH-PEG1-COOH
Thalidomide-NH-PEG1-C2-COOH
Propanoic acid, 3-[2-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethoxy]-
3-(2-((2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)ethoxy)propanoic acid, Crosslinker–E3 Ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
Thalidomide-4-NH-PEG1-C2-COOH
Poma-PEG1-COOH
Pomalidomide 4'-PEG1-acid
3-[2-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]ethoxy]propanoic Acid
2139348-60-8
peg