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Pomalidomide-PEG2-N3

CAS No.
2267306-14-7
Chemical Name:
Pomalidomide-PEG2-N3
Synonyms
N3-PEG2-CH2CO-Poma;Pomalidomide-PEG2-N3;Pomalidomide-NH-CO-PEG2-N3;2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber:
CB78118456
Molecular Formula:
C19H20N6O7
Molecular Weight:
444.4
MDL Number:
MFCD32198604
MOL File:
2267306-14-7.mol
Last updated:2024-07-02 08:55:17

Pomalidomide-PEG2-N3 Properties

Melting point 188 °C
storage temp. 2-8°C
solubility DMSO: 90 mg/mL (202.52 mM)
form Solid
color Off-white to light yellow

Pomalidomide-PEG2-N3 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 903833 Pomalidomide-PEG2-azide 2267306-14-7 50MG $538.2 2024-03-01 Buy
Iris Biotech GmbH PTC1530 Pomalidomid-PEG2-N3 2267306-14-7 50mg $607.5 2021-12-16 Buy
Product number Packaging Price Buy
903833 50MG $538.2 Buy
PTC1530 50mg $607.5 Buy

Pomalidomide-PEG2-N3 Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-PEG2-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

Pomalidomide-PEG2-N3 Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-PEG2-N3 Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2996 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9887 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4824 58
Jiangsu aikang biomedical research and development co., LTD 025-66110311 13155353615 qzhang@aikonchem.com China 15527 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1381 58
Shaanxi borno biotechnology co., LTD +86-13759708231 asherw9@hotmail.com China 2351 58
Shanghai Kaiwei Chemical Technology Co., Ltd. 021-58461859 15821823057 service@aiviche.com China 49323 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39997 58

View Lastest Price from Pomalidomide-PEG2-N3 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-NH-CO-PEG2-N3 pictures 2024-04-02 Pomalidomide-NH-CO-PEG2-N3
2267306-14-7
US $0.00 / mg 500mg >99.00% 500mg Xian confluore Biological Technology Co., Ltd.
Pomalidomide-PEG2-N3 Pomalidomide-NH-CO-PEG2-N3 2-(2-(2-Azidoethoxy)ethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide, Crosslinker?E3 ligase ligand conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader N3-PEG2-CH2CO-Poma 2267306-14-7