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Pomalidomide-PEG5-CO2H

CAS No.
2139348-63-1
Chemical Name:
Pomalidomide-PEG5-CO2H
Synonyms
Pomalidomide-PEG5-COOH;Pomalidomide-PEG5-CO2H;Pomalidomide 4'-PEG5-acid;POMALIDOMIDE-PEG 5-CO 2 H;Pomalidomide 4'-PEG5-acid;Thalidomide-NH-PEG5-C2-COOH;Pomalidomide-PEG5-CO2H >=98%;Pomalidomide-PEG5-CO2H ISO 9001:2015 REACH;1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12,15-pentaoxaoctadecan-18-oic Acid;1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid
CBNumber:
CB14846412
Molecular Formula:
C26H35N3O11
Molecular Weight:
565.57
MDL Number:
MFCD32173790
MOL File:
2139348-63-1.mol
MSDS File:
SDS
Last updated:2024-07-02 08:55:01

Pomalidomide-PEG5-CO2H Properties

Boiling point 791.0±60.0 °C(Predicted)
Density 1.360±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 4.28±0.10(Predicted)
form Solid-Liquid Mixture
color White to yellow

Pomalidomide-PEG5-CO2H price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 901828 Pomalidomide-PEG5-CO2H ≥95% 2139348-63-1 50MG $269.2 2024-03-01 Buy
Tocris 7095 Pomalidomide4'-PEG5-acid ≥95%(HPLC) 2139348-63-1 25 $269 2021-12-16 Buy
Iris Biotech GmbH PTC1190 Pomalidomide-PEG5-COOH 2139348-63-1 50mg $594 2021-12-16 Buy
Product number Packaging Price Buy
901828 50MG $269.2 Buy
7095 25 $269 Buy
PTC1190 50mg $594 Buy

Pomalidomide-PEG5-CO2H Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-PEG5-CO2H enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant carboxylic acid for reactivity with an amine on the target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant carboxyl group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

storage

Store at -20°C

Pomalidomide-PEG5-CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-PEG5-CO2H Suppliers

Global( 31)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences
+1-631-485-4226 inquiry@bocsci.com United States 19553 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 22883 58
LEAPCHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 43340 58
Nanjing Bicbiotechnology Co., Ltd
+86-2552131256 +86-18251840740 sales@bicbiotech.com China 5994 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2995 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 57505 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-400-6206333 18521732826 market@aladdin-e.com China 25003 65
Mashilabs (Shanghai) Co.,Ltd. 19916721580 mafarm@126.com China 4307 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51456 80
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12306 58

View Lastest Price from Pomalidomide-PEG5-CO2H manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-PEG5-COOH pictures 2024-04-02 Pomalidomide-PEG5-COOH
2139348-63-1
US $0.00 / mg 250mg >99.00% 250mg Xian confluore Biological Technology Co., Ltd.
Pomalidomide-PEG5-CO2H  pictures 2022-07-16 Pomalidomide-PEG5-CO2H
2139348-63-1
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
POMALIDOMIDE-PEG 5-CO 2 H Pomalidomide-PEG5-CO2H Propanoic acid, 3-[[14-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12-tetraoxatetradec-1-yl]oxy]- Pomalidomide-PEG5-CO2H >=98% Pomalidomide-PEG5-COOH Pomalidomide-PEG5-CO2H ISO 9001:2015 REACH Pomalidomide 4'-PEG5-acid 1-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)-3,6,9,12,15-pentaoxaoctadecan-18-oic acid Thalidomide-NH-PEG5-C2-COOH 1-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxo-4-isoindolinyl]amino]-3,6,9,12,15-pentaoxaoctadecan-18-oic Acid Pomalidomide 4'-PEG5-acid 1-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}-3,6,9,12,15-pentaoxaoctadecan-18-oic acid 2139348-63-1 peg