(15R)-18,21-ジデヒドロ-17-デメトキシ-18,21-ジデオキソ-18,21-ジヒドロキシ-15-メトキシゲルダナマイシン 化学特性,用途語,生産方法
説明
TAN 420C is a hydroquinone ansamycin antibiotic originally isolated from
Streptomyces. It exhibits antibacterial activity against
B. brevis and
M. flavus (MICs = 50 and 25 μg/mL, respectively). Additionally, it inhibits proliferation in the lymphocytic leukemia cell lines P388 and KB (ED
50s = 0.34 and 3.49 μg/mL, respectively).
使用
TAN 420C is a minor analogue of the herbimycin complex, isolated from Streptomyces hygroscopicus. TAN 420C is the hydroquinone of herbimycin C, and is known to exhibit antitumour activity. TAN 420C converts Rous sarcoma virus-infected rat kidney cells into normal cells.
(15R)-18,21-ジデヒドロ-17-デメトキシ-18,21-ジデオキソ-18,21-ジヒドロキシ-15-メトキシゲルダナマイシン 上流と下流の製品情報
原材料
準備製品