グアノシン5'-(二りん酸P2-チオホスホノ) 化学特性,用途語,生産方法
使用
GTP-γ-S has been used:
- in G-Protein activation assay to assess the functionality of protease-activated receptor 4 (PAR4)
- in fluorimetric guanine nucleotide exchange assay of G protein alpha subunits (Gα)
- to monitor the Rac family small guanosine triphosphatase (GTPase) 2 (Rac2)-stimulated activity of phospholipase Cγ2 mutants
一般的な説明
Guanosine 5′-
O-(3-thiotriphosphate), tetralithium salt (GTP-γ-S) is a non-hydrolysable analog of GTP. It is an inhibitor of phosphodiesterase in photoreceptors.
Biochem/physiol Actions
Guanosine 5′-O-(3-thiotriphosphate) (GTP-γ-S) activates guanine-nucleotide-binding proteins and is slowly hydrolyzed enzymatically. It inhibits guanosine triphosphatase (GTPases) more potently than guanosine triphosphate (GTP),
グアノシン5'-(二りん酸P2-チオホスホノ) 上流と下流の製品情報
原材料
準備製品