GGTI 298 trifluoroacetate salt hydrate
GGTI 298 trifluoroacetate salt hydrate 物理性質
- 融点 :
- 99.5-100°C
- 貯蔵温度 :
- -20°C
- 溶解性:
- DMSO：>20mg/mL
- 外見 :
- フィルム &_& 凍結乾燥
- 色:
- 無色
GGTI 298 trifluoroacetate salt hydrate 価格
もっと(3)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC2430 |
GGTI 298 |
1217457-86-7 |
1mg |
￥74000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G5169 |
GGTI-298トリフルオロ酢酸塩 トリフルオロアセタート塩 水和物 ≥90% (HPLC), film
GGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film |
1217457-86-7 |
1mg |
￥76100 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G5169 |
≥90% (HPLC), film
GGTI 298 trifluoroacetate salt hydrate ≥90% (HPLC), film |
1217457-86-7 |
.25mg |
￥16200 |
2018-12-25 |
購入 |
GGTI 298 trifluoroacetate salt hydrate 化学特性,用途語,生産方法
使用
GGTI 298 trifluoroacetate salt hydrate has been used as a geranylgeranyltransferase I (GGTase I) inhibitor:
- to study the anticancer effects of statins along with GGTI 298
- to study its combinatorial effects with FTI-277 on statin-mediated activation of extracellular signal-regulated kinase 5 (ERK5) in the human endothelium
- to evaluate the effect of protein geranylgeranylation (GG) inhibition on the breast cancer stem cell (CSC) population
Biochem/physiol Actions
GGTI 298 is a cell-permeable, prodrug form of the geranylgeranyltransferase I (GGTase I) inhibitor GGTI-297. It inhibits the processing of Rap 1A without effecting the processing of H-Ras.
GGTI 298 trifluoroacetate salt hydrate 上流と下流の製品情報
原材料
準備製品
GGTI 298 trifluoroacetate salt hydrate 生産企業
Global( 47)Suppliers
1217457-86-7()キーワード:
- 1217457-86-7
- GGTI 298 trifluoroacetate salt hydrate
- N-[[4-(2-(R)-Amino-3-mercaptopropyl)amino]-2-naphthylbenzoyl]leucine methyl ester trifluoroacetate salt hydrate
- GGTI-298 TFA
- GGTI298 Trifluoroacetate
- WALKWJPZELDSKT-UFABNHQSSA-N
- GGTI 298 TFA salt
- GGTI 298 TFA SALT;GGTI 298 (TRIFLUOROACETATE SALT)
- (S)-Methyl 2-(4-(((R)-2-amino-3-mercaptopropyl)amino)-2-(naphthalen-1-yl)benzamido)-4-methylpentanoate 2,2,2-trifluoroacetate