2,2',2'',2'''-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール

2,2',2'',2'''-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

2,2',2'',2'''-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール 化学特性,用途語,生産方法

Originator

Rapenton,Thomae,W. Germany,1980

Manufacturing Process

3.9 g (0.06 mol) of zinc powder were introduced into a solution of 5.0 g (0.01 mol) of 2,6-bis-(diethanolamino)-4,8-dipiperidino-pyrimido-[5,4-d]-pyrimidine (dipyridamole; see entry under that name for its synthesis) in 120 cc of aqueous 10% formic acid. The resulting mixture was heated on a water bath, while occasionally stirring, until the intense yellow color of the starting compound disappeared, which occurred after about 30 to 40 minutes. Thereafter, the unconsumed zinc powder was separated by vacuum filtration, the virtually colorless filtrate was essentially an aqueous solution of 2,6-bis- (diethanolamino)-8-piperidino-1,2,3,4-tetrahydropyrimido-[5,4-d]pyrimidine.
The filtrate was adjusted to a pH of 9 by adding concentrated ammonia, and then a 1 N aqueous iodine-potassium iodide solution was added dropwise, whereby the tetrahydropyrimido[5,4-d]pyrimidine obtained by hydrogenation with zinc in formic acid was converted by oxidation into 2,6-bis- (diethanolamino)-8-piperidino-pyrimido-[5,4-d]-pyrimidine. The completion of the oxidation was checked by means of a starch solution. The major amount of the oxidation product already separated out as a deep yellow crystalline precipitate during the addition of the iodine solution. After the oxidation reaction was complete, the reaction mixture was allowed to stand for a short period of time, and then the precipitate was separated by vacuum filtration,washed with water and dried. It had a melting point of 157°C to 158°C. The yield was 8.0 g, which corresponds to 95% theory.

Therapeutic Function

Platelet aggregation inhibitor

2,2',2'',2'''-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール 上流と下流の製品情報

原材料

準備製品

2,2',2'',2'''-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Shaanxi Dideu Newmaterial Co., Ltd.	029-87576359 15353716720	1039@dideu.com	China	10011	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11975	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19696	58

13665-88-8(2,2',2'',2'''-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール)キーワード:

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• 13665-88-8
• mopidamol
• 2,2',2'',2'''-[(4-Piperidinopyrimido[5,4-d]pyrimidine-2,6-diyl)dinitrilo]tetrakisethanol
• 2,2',2'',2'''-[[4-(1-Piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakisethanol
• 2,2',2'',2'''-[[4-Piperidinopyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetraethanol
• Compound RA-233
• RA-233
• Ethanol, 2,2',2'',2'''-[[4-(1-piperidinyl)pyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo]tetrakis- (9CI)
• Rapenton
• 化合物RA-233
• 2,2',2'',2'''-[[4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル]ジニトリロ]テトラエタノール
• モピダモール
• 2,2',2'',2'''-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール
• 2,2',2'',2'''-[[4-(1-ピペリジニル)ピリミド[5,4-d]ピリミジン-2,6-ジイル]ジニトリロ]テトラキスエタノール
• 2,2′,2′′,2′′′-[[4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル]ジニトリロ]テトラエタノール
• 2,2′,2′′,2′′′-[[4-(1-ピペリジニル)ピリミド[5,4-d]ピリミジン-2,6-ジイル]ジニトリロ]テトラキスエタノール
• 2-({6-[ビス(2-ヒドロキシエチル)アミノ]-8-(ピペリジン-1-イル)ピリミド[5,4-d][1,3]ジアジン-2-イル}(2-ヒドロキシエチル)アミノ)エタン-1-オール
• 2,2′,2′′,2′′′-[(4-ピペリジノピリミド[5,4-d]ピリミジン-2,6-ジイル)ジニトリロ]テトラキスエタノール