ヨウ化MPP+
ヨウ化MPP+ 物理性質
- 融点 :
- 166-168 °C
- 貯蔵温度 :
- desiccated
- 溶解性:
- 0.1 M HCl: 可溶
- 外見 :
- 個体
- 色:
- 黄色
- InChIKey:
- RFDFRDXIIKROAI-UHFFFAOYSA-M
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
D048 |
ヨウ化MPP+ ≥98% (HPLC), powder
MPP+ iodide ≥98% (HPLC), powder |
36913-39-0 |
100mg |
￥37700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
D048 |
ヨウ化MPP+ ≥98% (HPLC), powder
MPP+ iodide ≥98% (HPLC), powder |
36913-39-0 |
1g |
￥227000 |
2024-03-01 |
購入 |
ヨウ化MPP+ 化学特性,用途語,生産方法
使用
MPP+ iodide is an active metabolite of the dopaminergic neurotoxin MPTP.
一般的な説明
1-Methyl-4-phenylpyridinium (MPP+) induces neurotoxicity by inhibiting mitochondrial redox functions in the striatal synaptosomes. It is a potential neurotoxin and induces Parkinson′s disease in animal models. It mediates apoptosis by the generation of reactive oxygen species in cerebellar granule neurons and neuroblastoma cells. MPP+ modulates the distribution of dopamine. It elicits neurotoxicity by activating neuronal nitric oxide synthase (nNOS), resulting in excess nitric oxide.
Biochem/physiol Actions
MPP+ iodide is an active metabolite of dopaminergic neurotoxin MPTP.
ヨウ化MPP+ 上流と下流の製品情報
原材料
準備製品
ヨウ化MPP+ 生産企業
Global( 84)Suppliers
36913-39-0(ヨウ化MPP+)キーワード:
- 36913-39-0
- N-Methyl-4-phenylpyridinium iodide
- Pyridinium, 1-methyl-4-phenyl-, iodide
- MPP+ iodide,1-Methyl-4-phenylpyridinium iodide
- 1-methyl-4-phenyl-pyridiniuiodide
- MPP+ IODIDE (ACTIVE METABOLITE OF DOPAMI NERGIC NEUROTOX
- 4-phenylpyridin-1-ium iodide
- MPP+ IODIDE ISO 9001：2015 REACH
- 1-methyl-4-phenylpyridin-1-ium
- 4-phenylpyridinium iodide
- 1-Methyl-4-phenylpyridin-1-iuM iodide
- MPP+,Mitochondrial Metabolism,dopaminergic,neurons,MPP+ iodide,respiratory,chain,Inhibitor,inhibit,neurotoxic,complex
- 4-phenyl-N-methylpyridinium iodide
- Cyperquat iodide
- ヨウ化MPP+
- 1-メチル-4-フェニルピリジニウム・ヨージド