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テオドレナリン

テオドレナリン 化学構造式
13460-98-5
CAS番号.
13460-98-5
化学名:
テオドレナリン
别名:
テオドレナリン;7-[2-[[2-(3,4-ジヒドロキシフェニル)-2-ヒドロキシエチル]アミノ]エチル]テオフィリン;7-[2-[[2-(3,4-ジヒドロキシフェニル)-2-ヒドロキシエチル]アミノ]エチル]-3,7-ジヒドロ-1,3-ジメチル-1H-プリン-2,6-ジオン;7-(2-{[2-(3,4-ジヒドロキシフェニル)-2-ヒドロキシエチル]アミノ}エチル)-1,3-ジメチル-2,3,6,7-テトラヒドロ-1H-プリン-2,6-ジオン
英語名:
Theodrenaline
英語别名:
Theodrenaline;7-[2-[[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]theophyline;7-[2-[[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione;1H-Purine-2,6-dione, 7-[2-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]-3,7-dihydro-1,3-dimethyl-
CBNumber:
CB51179351
化学式:
C17H21N5O5
分子量:
375.38
MOL File:
13460-98-5.mol

テオドレナリン 物理性質

沸点 :
723.6±70.0 °C(Predicted)
比重(密度) :
1.51±0.1 g/cm3(Predicted)
貯蔵温度 :
Store at -20°C
溶解性:
Soluble in DMSO
酸解離定数(Pka):
9.59±0.10(Predicted)

安全性情報

テオドレナリン 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

テオドレナリン 化学特性,用途語,生産方法

効能

強心薬

Originator

Theodrenaline,ZYF Pharm Chemical

Manufacturing Process

A solution of 27 g of ω-chloroacetopyrocatechol in 150 ml of ethyl alcohol is added dropwise within 2 hours into a stirred and refluxed solution of 81 g of 7-(β-aminoethyl)theophylline in 200 ml of a 60% aqueous ethyl alcohol. Following this, boiling is continued for another 3.5 hours while passing through nitrogen, and the precipitated product is separated by suction filtration, washed with water and dried. The product is suspended in alcohol, admixed with alcoholic hydrochloric acid while heating until an acid reaction is observed and subjected to suction filtration after cooling. Obtained in this manner are 37 g of 7-[β-(β'-3,4-dihydroxyphenyl-β'- oxoethylamino)ethyl]theophylline hydrochloride having a melting point of 246- 249°C. To obtain an analytically pure product, the hydrochloride is dissolved in water and precipitated with acetone.
7.1 g of 7-[β-(β'-3,4-dihydroxyphenyl-β'-oxoethylamino)ethyl]theophylline hydrochloride are dissolved in 500 ml of distilled water and hydrogenated at 48°C in the presence of 1 g of platinum oxide. When no further hydrogen is absorbed after about 5 hours, the mixture is evaporated to dryness in vacuo. Purification is effected by taking up in methyl alcohol and mixing with ethyl acetate. Theodrenaline which has crystallized after several days is separated by suction filtration and dried in a desiccator. A product having a melting point of 176- 178°C is obtained in amount of 6.1 g.

Therapeutic Function

Analeptic

テオドレナリン 上流と下流の製品情報

原材料

白金(IV)ジオキシド

準備製品

テオドレナリン 生産企業

Global( 11)Suppliers
名前 電話番号 電子メール 国籍 製品カタログ 優位度
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000
 marketing@targetmol.com United States 19892 58
MedChemexpress LLC 021-58955995
sales@medchemexpress.cn United States 4863 58
BOC Sciences --
 info@bocsci.com USA 0 65
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223;
 psaitong@jm-bio.com China 29778 58
TargetMol Chemicals Inc. 4008200310
 marketing@tsbiochem.com China 24017 58
Hubei Enxing Biotechnology Co., Ltd 16621771607
 exbio_tech@163.com China 8324 58
RD International Technology Co., Limited 18024082417
 market@ubiochem.com China 9294 58

13460-98-5(テオドレナリン)キーワード:

テオドレナリン 1,3-ジメチル-7-(2-アミノエチル)-3,7-ジヒドロ-1H-プリン-2,6-ジオン
  • 13460-98-5
  • 7-[2-[[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
  • 7-[2-[[2-(3,4-Dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]theophyline
  • 1H-Purine-2,6-dione, 7-[2-[[2-(3,4-dihydroxyphenyl)-2-hydroxyethyl]amino]ethyl]-3,7-dihydro-1,3-dimethyl-
  • Theodrenaline
  • テオドレナリン
  • 7-[2-[[2-(3,4-ジヒドロキシフェニル)-2-ヒドロキシエチル]アミノ]エチル]テオフィリン
  • 7-[2-[[2-(3,4-ジヒドロキシフェニル)-2-ヒドロキシエチル]アミノ]エチル]-3,7-ジヒドロ-1,3-ジメチル-1H-プリン-2,6-ジオン
  • 7-(2-{[2-(3,4-ジヒドロキシフェニル)-2-ヒドロキシエチル]アミノ}エチル)-1,3-ジメチル-2,3,6,7-テトラヒドロ-1H-プリン-2,6-ジオン
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