(R)-SLV 319

656827-86-0

CAS番号.: 656827-86-0

化学名:

别名:

英語名:: (R)-SLV 319

英語别名:: (R)-SLV 319;SLV 319, (R)-(+)-;(4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide;4-chloro-N-{[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-methylamino-methylene}-benzenesulfonamide;1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4R)-

CBNumber:: CB52453032

化学式:: C23H20Cl2N4O2S

分子量:: 487.4

MOL File:: 656827-86-0.mol

物理性質

安全性情報

用途語

生産企業 27

(R)-SLV 319 物理性質

沸点 :: 623.2±65.0 °C(Predicted)

比重(密度) :: 1.38±0.1 g/cm3(Predicted)

貯蔵温度 :: Store at -20°C

溶解性:: ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide

外見 :: crystalline solid

酸解離定数(Pka):: 11?+-.0.60(Predicted)

安全性情報

(R)-SLV 319 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

(R)-SLV 319 化学特性,用途語,生産方法

説明

Central cannabinoid (CB₁) receptor antagonists may have potential in the treatment of a number of diseases such as neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction, and gastrointestinal disorders. (R)-SLV 319 is the inactive enantiomer of SLV 319 with 100-fold less affinity for the CB₁ receptor. SLV 319 is a potent and selective CB₁ receptor antagonist with K_i values of 7.8 and 7,943 nM for CB₁ and peripheral cannabinoid (CB₂) receptors, respectively. SLV 319 is less lipophilic (log P = 5.1) and therefore more water soluble than other known CB₁ receptor ligands.

(R)-SLV 319 上流と下流の製品情報

原材料

準備製品

(R)-SLV 319 生産企業

Global( 27)Suppliers

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9708	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
Anqing Rong Chuang Biological Technology Co., Ltd.	15001988657	1367753897@qq.com	China	945	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24017	58
Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd	18162595016	3287908757@qq.com	China	9887	58
ApexBio Technology	--	sales@apexbt.com	United States	6254	58

656827-86-0
(R)-SLV 319
(4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide
4-chloro-N-{[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-methylamino-methylene}-benzenesulfonamide
1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4R)-
SLV 319, (R)-(+)-