(R)-SLV 319

(R)-SLV 319 구조식 이미지
카스 번호:
656827-86-0
상품명:
(R)-SLV 319
동의어(영문):
(R)-SLV 319;SLV 319, (R)-(+)-;(4R)-5-(4-chlorophenyl)-N-(4-chlorophenyl)sulfonyl-N'-methyl-4-phenyl-3,4-dihydropyrazole-2-carboximidamide;4-chloro-N-{[3-(4-chloro-phenyl)-4-phenyl-4,5-dihydro-pyrazol-1-yl]-methylamino-methylene}-benzenesulfonamide;1H-Pyrazole-1-carboximidamide, 3-(4-chlorophenyl)-N-[(4-chlorophenyl)sulfonyl]-4,5-dihydro-N'-methyl-4-phenyl-, (4R)-
CBNumber:
CB52453032
분자식:
C23H20Cl2N4O2S
포뮬러 무게:
487.4
MOL 파일:
656827-86-0.mol

(R)-SLV 319 속성

끓는 점
623.2±65.0 °C(Predicted)
밀도
1.38±0.1 g/cm3(Predicted)
저장 조건
Store at -20°C
용해도
≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
물리적 상태
결정질 고체
산도 계수 (pKa)
11?+-.0.60(Predicted)

안전

(R)-SLV 319 C화학적 특성, 용도, 생산

개요

Central cannabinoid (CB1) receptor antagonists may have potential in the treatment of a number of diseases such as neuroinflammatory disorders, cognitive disorders, septic shock, obesity, psychosis, addiction, and gastrointestinal disorders. (R)-SLV 319 is the inactive enantiomer of SLV 319 with 100-fold less affinity for the CB1 receptor. SLV 319 is a potent and selective CB1 receptor antagonist with Ki values of 7.8 and 7,943 nM for CB1 and peripheral cannabinoid (CB2) receptors, respectively. SLV 319 is less lipophilic (log P = 5.1) and therefore more water soluble than other known CB1 receptor ligands.

(R)-SLV 319 준비 용품 및 원자재

원자재

준비 용품


(R)-SLV 319 공급 업체

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