RAS INHIBITORY PEPTIDE

159088-48-9

CAS番号.: 159088-48-9

化学名:

别名:

英語名:: RAS INHIBITORY PEPTIDE

英語别名:: VPPPVPPRRR-NH2;RAS INHIBITORY PEPTIDE;Sos SH3 domain inhibitor;Sos SH3 domain inhibitor inhibitor;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-

CBNumber:: CB5356014

化学式:: C53H91N19O11

分子量:: 1170.41

MOL File:: 159088-48-9.mol

物理性質

安全性情報

用途語

生産企業 48

RAS INHIBITORY PEPTIDE 物理性質

比重(密度) :: 1.52±0.1 g/cm3(Predicted)

貯蔵温度 :: −20°C

溶解性:: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml

外見 :: A crystalline solid

酸解離定数(Pka):: 3.31±0.10(Predicted)

安全性情報

WGK Germany	3

RAS INHIBITORY PEPTIDE 価格

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入

RAS INHIBITORY PEPTIDE 化学特性,用途語,生産方法

説明

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

RAS INHIBITORY PEPTIDE 上流と下流の製品情報

原材料

準備製品

RAS INHIBITORY PEPTIDE 生産企業

Global( 48)Suppliers

名前	電話番号	電子メール	国籍	製品カタログ	優位度
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10312	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42959	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
Chengdu Youngshe Chemical Co., Ltd.	+86-17380623303 +86-17380623303	Caroline@youngshechem.com	China	4900	58
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919	eric@peptidego.com	China	6526	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19105	58

159088-48-9
RAS INHIBITORY PEPTIDE
VPPPVPPRRR-NH2
VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG
H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH
HSOS (1149-1158) N10 SH3 BINDING DOMAIN
Sos SH3 domain inhibitor
L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
Sos SH3 domain inhibitor inhibitor