RAS INHIBITORY PEPTIDE

159088-48-9

CAS-Nr.: 159088-48-9

Englisch Name:: RAS INHIBITORY PEPTIDE

Synonyma:: VPPPVPPRRR-NH2;RAS INHIBITORY PEPTIDE;Sos SH3 domain inhibitor;Sos SH3 domain inhibitor inhibitor;VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG;HSOS (1149-1158) N10 SH3 BINDING DOMAIN;H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH;L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-

CBNumber:: CB5356014

Summenformel:: C53H91N19O11

Molgewicht:: 1170.41

MOL-Datei:: 159088-48-9.mol

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Eigenschaften Sicherheit Verwendungswort Produktionsfirma 48

RAS INHIBITORY PEPTIDE Eigenschaften

Dichte: 1.52±0.1 g/cm3(Predicted)

storage temp.: −20°C

Löslichkeit: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: Miscible; PBS (pH 7.2): 10 mg/ml

Aggregatzustand: A crystalline solid

pka: 3.31±0.10(Predicted)

Sicherheit

WGK Germany	3

RAS INHIBITORY PEPTIDE Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Son of sevenless homolog 1 (Sos1) is a guanine nucleotide exchange factor (GEF) that directs the exchange of Ras-GDP to Ras-GTP by binding to SH3 domains of the growth factor receptor-bound protein 2 (Grb2), leading to the activation of ERK. Ras inhibitory peptide is a synthetic peptide that contains the sequence PVPPR, which corresponds to a region within human Sos1 that interacts with an SH3 domain of Grb2. It specifically blocks the interaction of the GEF with Grb2, preventing an interaction that is essential for Ras activation by receptor tyrosine kinases, including epidermal growth factor receptor.

RAS INHIBITORY PEPTIDE Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

RAS INHIBITORY PEPTIDE Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 48)Lieferanten

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10318	58
Zhejiang Hangyu API Co., Ltd	+8617531972939	anna@api-made.com	China	2944	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
GL Biochem (Shanghai) Ltd	21-61263452 13641803416	ymbetter@glbiochem.com	China	9981	64
Shanghai Hanhong Scientific Co.,Ltd.	021-54306202 13764082696	info@hanhongsci.com	China	42981	64
Chemsky (shanghai) International Co.,Ltd	021-50135380	shchemsky@sina.com	China	15421	60
Chengdu Youngshe Chemical Co., Ltd.	+86-17380623303 +86-17380623303	Caroline@youngshechem.com	China	5392	58
Hangzhou Peptidego Biotech Co.,Ltd.	0571-87213919	eric@peptidego.com	China	6526	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
Nanjing Meihao Pharmaceutical Technology Co., Ltd.	meitaochem@126.com	meitaochem@126.com	China	19105	58

RAS INHIBITORY PEPTIDE
VPPPVPPRRR-NH2
VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG
H-VAL-PRO-PRO-PRO-VAL-PRO-PRO-ARG-ARG-ARG-OH
HSOS (1149-1158) N10 SH3 BINDING DOMAIN
Sos SH3 domain inhibitor
L-Arginine, L-valyl-L-prolyl-L-prolyl-L-prolyl-L-valyl-L-prolyl-L-prolyl-L-arginyl-L-arginyl-
Sos SH3 domain inhibitor inhibitor
159088-48-9
C53H91N19O11
BioChemical
Cell Signaling and Neuroscience
Cell Biology
Reagents
G Protein Function
G Proteins and Cyclic Nucleotides