1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE

 化学構造式
288862-73-7
CAS番号.
288862-73-7
化学名:
别名:
英語名:
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
英語别名:
CAY10435;1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE;1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-;1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
CBNumber:
CB5423194
化学式:
C18H26N2O2
分子量:
302.41
MOL File:
288862-73-7.mol

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE 物理性質

沸点 :
420.9±37.0 °C(Predicted)
比重(密度) :
1.044±0.06 g/cm3(Predicted)
溶解性:
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): .05mg/ml; Ethanol: 10 mg/ml
酸解離定数(Pka):
-1.77±0.50(Predicted)

安全性情報

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE 価格

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE 化学特性,用途語,生産方法

説明

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.57 nM. Using a proteonomics approach, CAY10435 was screened against the serine hydrolase family of enzymes, of which FAAH is a member. In this assay, CAY10435 exhibited IC50 values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Knowledge of the specificity of CAY10435 obtained from this experiment should allow for more accurate interpretation of results using the inhibitor in complex environments such as whole cells or animals.

1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE 上流と下流の製品情報

原材料

準備製品


1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE 生産企業

Global( 17)Suppliers
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288862-73-7()キーワード:


  • 288862-73-7
  • CAY10435
  • 1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
  • 1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
  • 1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-
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