1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논

1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논
1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논 구조식 이미지
카스 번호:
288862-73-7
한글명:
1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논
동의어(한글):
1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논
상품명:
1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE
동의어(영문):
CAY10435;1-OXAZOLO[4,5-B]PYRIDIN-2-YL-1-DODECANONE;1-Dodecanone, 1-oxazolo[4,5-b]pyridin-2-yl-;1-([1,3]oxazolo[4,5-b]pyridin-2-yl)dodecan-1-one
CBNumber:
CB5423194
분자식:
C18H26N2O2
포뮬러 무게:
302.41
MOL 파일:
288862-73-7.mol

1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논 속성

끓는 점
420.9±37.0 °C(Predicted)
밀도
1.044±0.06 g/cm3(Predicted)
용해도
DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2) (1:2): .05mg/ml; Ethanol: 10 mg/ml
산도 계수 (pKa)
-1.77±0.50(Predicted)

안전

1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논 C화학적 특성, 용도, 생산

개요

Fatty acid amide hydrolase (FAAH) is the enzyme responsible for hydrolysis and inactivation of fatty acid amides including anandamide and oleamide. CAY10435 is a selective, potent inhibitor of rat FAAH exhibiting a Ki value of 0.57 nM. Using a proteonomics approach, CAY10435 was screened against the serine hydrolase family of enzymes, of which FAAH is a member. In this assay, CAY10435 exhibited IC50 values of 0.81 nM, 83 nM, and 50 μM for FAAH, triacylglycerol hydrolase (TGH), and an uncharacterized hydrolase (KIAA1363), respectively. Knowledge of the specificity of CAY10435 obtained from this experiment should allow for more accurate interpretation of results using the inhibitor in complex environments such as whole cells or animals.

1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논 준비 용품 및 원자재

원자재

준비 용품


1-옥사졸로[4,5-B]피리딘-2-YL-1-도데카논 공급 업체

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