1,2-ジメチルヒドラジン 化学特性,用途語,生産方法
化学的特性
colourless or yellow hygroscopic liquid which fumes in air
使用
1,2-Dimethylhydrazine (SDMH) unlike its analog 1,1-
dimethylhydrazine (UDMH) is used only in small quantities
as a research chemical. There are no known commercial uses,
although it was evaluated as a high-energy rocket fuel. The
material is a fuming, strongly alkaline, moderately volatile
liquid.
定義
ChEBI: A member of the class of hydrazines that is hydrazine in which one of the hydrogens attached to each nitrogen is replaced by a methyl group. A powerful DNA alkylating agent and carcinogen, it is used to induce colon cancer in laboratory rats and mice.
一般的な説明
A colorless liquid with an ammonia-like odor. Less dense than water. Flash point is 5°F. Contact irritate skin, eyes, and mucous membranes. Very toxic by ingestion, inhalation and skin absorption. Used to make photographic chemicals.
空気と水の反応
Highly flammable. Fumes upon exposure to air . Soluble in water with evolution of heat.
反応プロフィール
1，2-Dimethyl hydrazine dissolves, swells, and disintegrates many plastics [USCG, 1999].
健康ハザード
Breathing of vapor causes pulmonary irritation, delayed gastro-intestinal irritation, tremors, and convulsions. Contact with skin or mucous membranes causes chemical burns. Can be absorbed through skin to cause systemic intoxication and convulsions.
安全性プロファイル
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic, and teratogenic
data. Poison by ingestion, intraperitoneal,
intravenous, subcutaneous, and
intramuscular routes. Moderately toxic by
inhalation. Human mutation data reported.
A very dangerous fire hazard when exposedto heat, flame, or oxidizers. A hgh-energy
propellant for liquid-fueled rockets. When
heated to decomposition it emits toxic
fumes of NOx
発がん性
SDMH is carcinogenic to mice,
rats, and hamsters using a variety of exposure routes. Oral
doses of 21 mg/kg for 11 weeks produced intestinal tumors
in rats. A lower dose (3 mg/kg) in drinking water for
12 months produced liver hemangioendotheliomas.A
number of these tumors were metastatic. Mice given
doses of 60–90 mg/day in drinking water developed a variety
of tumors including angiosarcomas and lung adenomas
. Both oral administration and intraperitoneal
injection increased lung adenomas in the A/J strain
mouse. Hamsters also developed angiosarcomas,
intestinal tumors, and liver tumors following average daily
intakes of 160 mg in drinking water. An in-depth
description of the uniqueness of the colonic tumors was
presented.
1,2-ジメチルヒドラジン 上流と下流の製品情報
原材料
準備製品