GW3965塩酸塩
GW3965塩酸塩 物理性質
- 貯蔵温度 :
- Store at -20°C
- 溶解性:
- DMSO：20mg/mL以上
- 外見 :
- 粉
- 色:
- 白い
- InChIKey:
- NMPUWJFHNOUNQU-UHFFFAOYSA-N
GW3965塩酸塩 価格
もっと(4)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC2474 |
GW3965塩酸塩
GW 3965 hydrochloride |
405911-17-3 |
1mg |
￥46000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01TOC2474 |
GW3965塩酸塩
GW 3965 hydrochloride |
405911-17-3 |
10mg |
￥98000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G6295 |
GW3965 塩酸塩 ≥98% (HPLC), powder
GW3965 hydrochloride ≥98% (HPLC), powder |
405911-17-3 |
5mg |
￥48600 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
G6295 |
GW3965 塩酸塩 ≥98% (HPLC), powder
GW3965 hydrochloride ≥98% (HPLC), powder |
405911-17-3 |
25mg |
￥159000 |
2024-03-01 |
購入 |
GW3965塩酸塩 化学特性,用途語,生産方法
使用
GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.
Biochem/physiol Actions
GW3965 is a liver X receptor full agonist on hLXRα and hLXRβ. GW3965 has an EC50 = 125 nM in a cell-free ligand-sensing assay of LXRα and profiles as a full agonist on hLXRα and hLXRβ in cell-based assays with EC50 = 190 nM and 30 nM, respectively. It is orally active in mice. When screened against a panel of nuclear receptors, it cross-reacted with only the pregnane X receptor (PXR). The literature agonist, T0901317 (Tularik), had an EC50 = 60 nM and 85 nM in the cell-free and cell-based assays, respectively.
GW3965塩酸塩 上流と下流の製品情報
原材料
準備製品
GW3965塩酸塩 生産企業
Global( 122)Suppliers
GW3965塩酸塩 スペクトルデータ(1HNMR)
405911-17-3(GW3965塩酸塩)キーワード:
- 405911-17-3
- 3-[3-[n-(2-chloro-3-trifluoromethylbenzyl)-(2,2-diphenylethyl)amino]propyloxy]phenylacetic acid hydrochloride
- 3-[3-[n-(2-chloro-3-trifluoroMethylbenzyl)-(2,2-di…
- GW3965 HCl
- 2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride
- GW3965 hydrochloride, >=98%
- Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride
- GW3965 HCl Salt
- 3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetic acid hydrochloride
- CS-742
- GW 3965 HYDROCHLORIDE; GW-3965 HYDROCHLORIDE;
- 3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenylacetic Acid Hydrochloride
- 2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylet...
- GW-3965 hydrochloride GW3965
- Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride (1:1)
- 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-Benzeneacetic acid hydrochloride (1:1)
- W 3965 HYDROCHLORIDE
- GW3965塩酸塩
- GW3965 塩酸塩