3-ブロモ-4-ピリジノール
3-ブロモ-4-ピリジノール 物理性質
- 融点 :
- 225-230℃
- 沸点 :
- 338.2±22.0 °C(Predicted)
- 比重(密度) :
- 1.788±0.06 g/cm3(Predicted)
- 貯蔵温度 :
- Inert atmosphere,Room Temperature
- 外見 :
- powder
- 酸解離定数(Pka):
- 3.71±0.18(Predicted)
- 色:
- light yellow
- CAS データベース:
- 36953-41-0(CAS DataBase Reference)
3-ブロモ-4-ピリジノール 価格
もっと(15)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBPY-7735 |
3-Bromopyridin-4-ol |
36953-41-0 |
1g |
￥10000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBPY-7735 |
3-Bromopyridin-4-ol |
36953-41-0 |
5g |
￥32500 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS071865 |
3-ブロモ-4-ピリジノール
3-Bromo-4-pyridinol |
36953-41-0 |
10g |
￥92000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS071865 |
3-ブロモ-4-ピリジノール
3-Bromo-4-pyridinol |
36953-41-0 |
1g |
￥16100 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01MAS071865 |
3-ブロモ-4-ピリジノール
3-Bromo-4-pyridinol |
36953-41-0 |
5g |
￥54300 |
2024-03-01 |
購入 |
3-ブロモ-4-ピリジノール 化学特性,用途語,生産方法
使用
3-Bromo-4-hydroxypyridine is a pyrrole that can be used in cancer treatment. It inhibits the growth of cancer cells by binding to MKN-45 on the cell surface, thereby preventing it from binding to other proteins and triggering cell proliferation.
合成
3-Bromo-4-hydroxypyridine is synthesized from 3-bromo-5 hydroxypyridine by reacting it with ammonia or methylamine.
Concentrated sulfuric acid (85.0mL) and the 3-bromo-4-aminopyridine (113.0g, 0.65mol) were added successively to the distilled water (550.0mL) at 0°C, and then NaNO2 (63.1g, 0.91mol) aqueous solution (130.0mL) was added drop-wise to maintain the temperature between 0 and 5°C. After stirring at r. t. for 1h, the reaction mixture was heated at 95°C for a further 0.5h. Upon cooling to below 0°C, the mixture was alkalized to pH 6 with saturated sodium hydroxide solution, washed with ethyl acetate (200mL×3) and brine (200mL), dried over anhydrous Na2SO4, filtered and concentrated to yield 3-Bromo-4-hydroxypyridine as a yellow solid (75.1g, 66.2percent).
3-ブロモ-4-ピリジノール 上流と下流の製品情報
原材料
準備製品
3-ブロモ-4-ピリジノール 生産企業
Global( 178)Suppliers
3-ブロモ-4-ピリジノール スペクトルデータ(FT-IR)
36953-41-0(3-ブロモ-4-ピリジノール)キーワード:
- 36953-41-0
- 3-BROMO-4-HYDROXYPYRIDINE
- 3-BROMO-4-PYRIDINOL
- 4-HYDROXY-3-BROMOPYRIDINE
- 3-BROMO-4-HYDROXYPYRIDINE 97%
- Synthesis of 3-bromopyridin-4-ol
- 4-Pyridinol, 3-bromo-
- 3-Bromo-4-hydroxypyridine,97%
- 3-Bromo-4-hydroxypyridine ISO 9001：2015 REACH
- 3-bromo-1H-pyridin-4-one
- 3-Bromopyridin-4-ol
- 3-ブロモ-4-ピリジノール