3-Bromo-4-hydroxypyridine
- CAS No.
- 36953-41-0
- Chemical Name:
- 3-Bromo-4-hydroxypyridine
- Synonyms
- 3-Bromopyridin-4-ol;3-BROMO-4-PYRIDINOL;4-Pyridinol, 3-bromo-;3-bromo-1H-pyridin-4-one;3-BROMO-4-HYDROXYPYRIDINE;4-HYDROXY-3-BROMOPYRIDINE;3-Bromo-4-hydroxypyridine,97%;3-BROMO-4-HYDROXYPYRIDINE 97%;Synthesis of 3-bromopyridin-4-ol;3-Bromo-4-hydroxypyridine ISO 9001：2015 REACH
- CBNumber:
- CB6110145
- Molecular Formula:
- C5H4BrNO
- Molecular Weight:
- 174
- MDL Number:
- MFCD01646107
- MOL File:
- 36953-41-0.mol
| Melting point | 225-230℃ |
|---|---|
| Boiling point | 338.2±22.0 °C(Predicted) |
| Density | 1.788±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Room Temperature |
| form | powder |
| pka | 3.71±0.18(Predicted) |
| color | light yellow |
| CAS DataBase Reference | 36953-41-0(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| HS Code | 2933399990 | |||||||||
| NFPA 704 |
|
3-Bromo-4-hydroxypyridine price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Alfa Aesar | H33754 | 3-Bromo-4-hydroxypyridine, 97% | 36953-41-0 | 1g | $208.65 | 2024-03-01 | Buy |
| Alfa Aesar | H33754 | 3-Bromo-4-hydroxypyridine, 97% | 36953-41-0 | 5g | $692.65 | 2024-03-01 | Buy |
| Alfa Aesar | H33754 | 3-Bromo-4-hydroxypyridine, 97% | 36953-41-0 | 250mg | $75.6 | 2021-12-16 | Buy |
| TRC | B698850 | 3-Bromopyridin-4-ol | 36953-41-0 | 250mg | $55 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB140263 | 3-Bromopyridin-4-ol | 36953-41-0 | 2g | $74 | 2021-12-16 | Buy |
3-Bromo-4-hydroxypyridine Chemical Properties,Uses,Production
Uses
3-Bromo-4-hydroxypyridine is a pyrrole that can be used in cancer treatment. It inhibits the growth of cancer cells by binding to MKN-45 on the cell surface, thereby preventing it from binding to other proteins and triggering cell proliferation.
Synthesis
3-Bromo-4-hydroxypyridine is synthesized from 3-bromo-5 hydroxypyridine by reacting it with ammonia or methylamine.
Concentrated sulfuric acid (85.0mL) and the 3-bromo-4-aminopyridine (113.0g, 0.65mol) were added successively to the distilled water (550.0mL) at 0°C, and then NaNO2 (63.1g, 0.91mol) aqueous solution (130.0mL) was added drop-wise to maintain the temperature between 0 and 5°C. After stirring at r. t. for 1h, the reaction mixture was heated at 95°C for a further 0.5h. Upon cooling to below 0°C, the mixture was alkalized to pH 6 with saturated sodium hydroxide solution, washed with ethyl acetate (200mL×3) and brine (200mL), dried over anhydrous Na2SO4, filtered and concentrated to yield 3-Bromo-4-hydroxypyridine as a yellow solid (75.1g, 66.2percent).
3-Bromo-4-hydroxypyridine Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5906 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5600 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8831 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14442 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from 3-Bromo-4-hydroxypyridine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-09-25 | 3-Bromo-4-hydroxypyridine
36953-41-0
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited | |
 |
2021-07-13 | 3-Bromo-4-hydroxypyridine
36953-41-0
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | 3-Bromo-4-hydroxypyridine
36953-41-0
|
US $3.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- 3-Bromo-4-hydroxypyridine
36953-41-0
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited
-
- 3-Bromo-4-hydroxypyridine
36953-41-0
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 3-Bromo-4-hydroxypyridine
36953-41-0
- US $3.00 / KG
- 99%
- Career Henan Chemical Co