ナフェノピン
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- CAS番号.
- 3771-19-5
- 化学名:
- ナフェノピン
- 别名:
- メリパン;2-メチル-2-[4-(1,2,3,4-テトラヒドロナフタレン-1-イル)フェノキシ]プロピオン酸;ナフェノピン;2-メチル-2-[p-(1,2,3,4-テトラヒドロナフタレン-1-イル)フェノキシ]プロピオン酸;2-メチル-2-[4-(1,2,3,4-テトラヒドロナフタレン-1-イル)フェノキシ]プロパン酸
- 英語名:
- Nafenopin
- 英語别名:
- TPIA;Melipan;Su-13437;Nafenopin;C-13437Su;CIBA-13437Su;Nafenopin USP/EP/BP;2-methyl-2-(4-tetralin-1-ylphenoxy)propionic acid;2-METHYL-2-PARA-(1,2,3,4-TETRAHYDRO-1-NAPHTHYL)PHENOXYPROPIONICACID;2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoicaci
- CBNumber:
- CB61116627
- 化学式:
- C20H22O3
- 分子量:
- 310.39
- MOL File:
- 3771-19-5.mol
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ナフェノピン 物理性質
- 融点 :
- 117-118 °C
- 沸点 :
- 390.55°C (rough estimate)
- 比重(密度) :
- 1.1662 (rough estimate)
- 屈折率 :
- 1.4618 (estimate)
- 貯蔵温度 :
- Sealed in dry,Room Temperature
- 酸解離定数(Pka):
- 3.28±0.10(Predicted)
- IARC:
- 2B (Vol. 24, Sup 7) 1987
- EPAの化学物質情報:
- Nafenopin (3771-19-5)
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
 
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| 注意喚起語 |
警告 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H302 |
飲み込むと有害 |
急性毒性、経口 |
4 |
警告 |
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P264, P270, P301+P312, P330, P501 |
| H351 |
発がんのおそれの疑い |
発がん性 |
2 |
警告 |
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P201, P202, P281, P308+P313, P405,P501 |
| H361 |
生殖能または胎児への悪影響のおそれの疑い |
生殖毒性 |
2 |
警告 |
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P201, P202, P281, P308+P313, P405,P501 |
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| 注意書き |
| P280 |
保護手袋/保護衣/保護眼鏡/保護面を着用するこ と。 |
| P305+P351+P338 |
眼に入った場合：水で数分間注意深く洗うこと。次にコ ンタクトレンズを着用していて容易に外せる場合は外す こと。その後も洗浄を続けること。 |
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ナフェノピン 価格
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
ナフェノピン 化学特性,用途語,生産方法
効能
脂質異常症治療薬
定義
ChEBI: A monocarboxylic acid that is 2-hydroxy-2-methylpropanoic acid in which ther tertiary hydroxy group has been converted to the corresponding p-(1,2,3,4-tetrahydronaphthalen-1-yl)phenyl ether.
一般的な説明
Crystals.
反応プロフィール
An organic acid. Carboxylic acids donate hydrogen ions if a base is present to accept them. They react in this way with all bases, both organic (for example, the amines) and inorganic. Their reactions with bases, called "neutralizations", are accompanied by the evolution of substantial amounts of heat. Neutralization between an acid and a base produces water plus a salt. Carboxylic acids in aqueous solution and liquid or molten carboxylic acids can react with active metals to form gaseous hydrogen and a metal salt. Such reactions occur in principle for solid carboxylic acids as well, but are slow if the solid acid remains dry. Even "insoluble" carboxylic acids may absorb enough water from the air and dissolve sufficiently in Nafenopin to corrode or dissolve iron, steel, and aluminum parts and containers. Carboxylic acids, like other acids, react with cyanide salts to generate gaseous hydrogen cyanide. The reaction is slower for dry, solid carboxylic acids. Insoluble carboxylic acids react with solutions of cyanides to cause the release of gaseous hydrogen cyanide. Flammable and/or toxic gases and heat are generated by the reaction of carboxylic acids with diazo compounds, dithiocarbamates, isocyanates, mercaptans, nitrides, and sulfides. Carboxylic acids, especially in aqueous solution, also react with sulfites, nitrites, thiosulfates (to give H2S and SO3), dithionites (SO2), to generate flammable and/or toxic gases and heat. Their reaction with carbonates and bicarbonates generates a harmless gas (carbon dioxide) but still heat. Like other organic compounds, carboxylic acids can be oxidized by strong oxidizing agents and reduced by strong reducing agents. These reactions generate heat. A wide variety of products is possible.
火災危険
Flash point data for Nafenopin are not available. Nafenopin is probably combustible.
安全性プロファイル
Confirmed carcinogen
with experimental carcinogenic and
tumorigenic data. Moderately toxic by
ingestion. Mutation data reported. A drug
for the treatment of hypercholesterolemia or
hypertriglyceridemia. When heated to
decomposition it emits acrid smoke and
irritating fumes.
ナフェノピン 上流と下流の製品情報
原材料
準備製品
ナフェノピン 生産企業
Global( 26)Suppliers
3771-19-5(ナフェノピン)キーワード:
- 3771-19-5
- Nafenopin
- 2-METHYL-2-PARA-(1,2,3,4-TETRAHYDRO-1-NAPHTHYL)PHENOXYPROPIONICACID
- C-13437Su
- CIBA-13437Su
- Melipan
- Su-13437
- TPIA
- 2-methyl-2-(4-tetralin-1-ylphenoxy)propionic acid
- 2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid
- Propanoic acid, 2-methyl-2-[4-(1,2,3,4-tetrahydro-1-naphthalenyl)phenoxy]-
- 2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoicaci
- Nafenopin USP/EP/BP
- メリパン
- 2-メチル-2-[4-(1,2,3,4-テトラヒドロナフタレン-1-イル)フェノキシ]プロピオン酸
- ナフェノピン
- 2-メチル-2-[p-(1,2,3,4-テトラヒドロナフタレン-1-イル)フェノキシ]プロピオン酸
- 2-メチル-2-[4-(1,2,3,4-テトラヒドロナフタレン-1-イル)フェノキシ]プロパン酸
- 脂質低下薬