エステラーゼ
エステラーゼ 物理性質
- 貯蔵温度 :
- 2-8°C
- 外見 :
- 粉
- 色:
- やや茶色
安全性情報
- リスクと安全性に関する声明
- 危険有害性情報のコード(GHS)
| 絵表示（GHS） |
|
| 注意喚起語 |
危険 |
| 危険有害性情報 |
| コード |
危険有害性情報 |
危険有害性クラス |
区分 |
注意喚起語 |
シンボル |
P コード |
| H334 |
吸入するとアレルギー、喘息または、呼吸困難 を起こすおそれ |
感作性、呼吸器 |
1 |
危険 |
|
P261, P285, P304+P341, P342+P311,P501 |
|
| 注意書き |
| P261 |
粉じん/煙/ガス/ミスト/蒸気/スプレーの吸入を避ける こと。 |
| P284 |
呼吸用保護具を着用すること。 |
| P501 |
内容物/容器を．．．に廃棄すること。 |
|
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
Sigma-Aldrich Japan
|
E0287 |
カルボキシエステラーゼ1アイソフォームb ヒト recombinant, expressed in baculovirus infected BTI insect cells
Carboxylesterase 1 isoform b human recombinant, expressed in baculovirus infected BTI insect cells |
9013-79-0 |
1vial |
￥83700 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
E0162 |
recombinant, expressed in baculovirus infected BTI insect cells
Carboxylesterase 1 isoform c human recombinant, expressed in baculovirus infected BTI insect cells |
9013-79-0 |
1vl |
￥54000 |
2018-12-25 |
購入 |
|
Sigma-Aldrich Japan
|
E0287 |
recombinant, expressed in baculovirus infected BTI insect cells
Carboxylesterase 1 isoform b human recombinant, expressed in baculovirus infected BTI insect cells |
9013-79-0 |
1vl |
￥61200 |
2018-12-25 |
購入 |
エステラーゼ 化学特性,用途語,生産方法
解説
エステル結合に作用する酵素の総称．カルボン酸，リン酸，チオリン酸などのエステル，チオエステルなどをそれぞれ加水分解する酵素がある．油脂を加水分解して脂肪酸を生成する酵素リパーゼは代表的な例である．
用途
製造用剤
使用
Carboxylesterase 1 isoform c human has been used as a reference standard in carboxylesterase activity from the mussel for comparison of substrate specificity and inhibition studies. It has also been used as a commercial recombinant protein for the methodological validation of environmental chemical-based inhibition studies.
一般的な説明
Carboxylesterase 1 is a member of a large multigene carboxylesterase family. These enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters. This enzyme is known to hydrolyze aromatic and aliphatic esters and is necessary for cellular cholesterol esterification. It may also play a role in detoxification in the lung and/or protection of the central nervous system from ester or amide compounds.
Biochem/physiol Actions
Carboxylesterase enzymes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolyze long-chain fatty acid esters and thioesters. Carboxylesterase 1 (CE1) catalyzes the formation of cholesteryl esters from cholesterol and fatty acids. Through a transesterification reaction, CE1 also mediates the generation of fatty acid ethyl esters (FAEEs). It also hydrolyzes aromatic and aliphatic esters with preference to small alcohol groups and bulky acyl groups. CE1 metabolizes drug esters and amides carbamates. It participates in the detoxification of environmental toxicants and carcinogens and is useful in pharmacokinetic studies for evaluating pro-drugs.
エステラーゼ 上流と下流の製品情報
原材料
準備製品
エステラーゼ 生産企業
Global( 2)Suppliers
9013-79-0(エステラーゼ)キーワード:
- 9013-79-0
- LIPASE CA
- Carboxylesterase 1 isoform b human
- Carboxylesterase 1 human
- Carboxylesterase 1 isoform c human
- CARBOXYLESTERASE, IMMOBILIZED
- CARBOXYLIC-ESTER HYDROLASE
- CARBOXYL ESTERASE
- EC 3.1.1.1
- HLE
- ESTERASE
- ESTERASE BS1
- ESTERASE BS2
- ESTERASE BS2-CLEA
- ESTERASE BS3
- ESTERASE BS4
- ESTERASE, FRACTION 1 (PIG LIVER)
- ESTERASE, FRACTION 2 (PIG LIVER)
- ESTERASE, IMMOBILIZED ON EUPERGIT(R) C
- ESTERASE, IMMOBILIZED ON OXIRAN ACRYLIC BEADS
- ESTERASE ISOENZYME 1
- ESTERASE PF1
- ESTERASE PF2
- ESTERASE (PIG LIVER)
- ESTERASE PL
- ESTERASE RO
- ESTERASE SD
- ESTERASE SOLUTION PORCINE LIVER
- ESTERASE TL
- PIG LIVER ESTERASE, IMMOBILIZED ON EUPERGIT(R) C
- PLE ON EUPERGIT(R) C
- エステラーゼ