NSC-23766

NSC-23766 価格 もっと(2)

メーカー	製品番号	製品説明	CAS番号	包装	価格	更新時間	購入
富士フイルム和光純薬株式会社(wako)	W01BVI1941-1	NSC 23766	733767-34-5	1mg	￥19500	2020-09-21	購入
富士フイルム和光純薬株式会社(wako)	W01BVI1941-5	NSC 23766	733767-34-5	5mg	￥63700	2020-09-21	購入

NSC-23766 化学特性,用途語,生産方法

使用

The compound blocks activation by the guanine nucleotide exchange factors Trio and Tiam1, but does not affect interactions with RhoA or Cdc42. NSC23766 blocks ADP-mediated platelet aggregation. Inhibition of Rac1 by NSC23766 restores sensitivity to trastuzumab by restoring down-regulation of ErbB2. Membrane type 1-matrix metalloproteinases (MT-1MMP) expression in CB CD34+ cells has been reported to decrease in the presence of NSC 23766. Silveta compress investigations indicate that NSC 23766 depolarizes endomembrane cycling, altered polar adhesive secretion, and tip growth.

生物活性

Selective inhibitor of Rac1-GEF interaction. Prevents Rac1 activation by Rac-specific guanine nucleotide exchange factors (GEFs) TrioN and Tiam1 (IC 50 ~ 50 μ M) without affecting Cdc42 or RhoA activation. Inhibits Rac1-mediated cell functions and reported to reverse tumor cell phenotyes in prostate cancer cells.

NSC-23766 上流と下流の製品情報

原材料

準備製品

NSC-23766 生産企業

名前	電話番号	電子メール	国籍	製品カタログ	優位度
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
Coresyn Pharmatech Co., Ltd.	+86-571-86626709 +86-18157142896	cbc@coresyn.com	China	9991	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131980	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
QINGDAO CARELONGPHARMATECH CO.,LTD	0532-0532-88191853 13061484198	sales@carelongchem.com	China	405	57
Shanghai Aladdin Bio-Chem Technology Co.,LTD	400-400-6206333 18521732826	market@aladdin-e.com	China	25014	65
TargetMol Chemicals Inc.	021-021-33632979 15002134094	marketing@targetmol.com	China	7854	58
AdooQ Bioscience CHINA	025-58849295 18951903616;	info@adooq.cn	China	2989	60

733767-34-5(NSC-23766)キーワード:

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• 733767-34-5
• NSC 23766 TETRAHYDROCHLORIDE
• N6-[2-[[4-(DIETHYLAMINO)-1-METHYLBUTYL]AMINO]-6-METHYL-4-PYRIMIDINYL]-2-METHYL-4,6-QUINOLINEDIAMINE TRIHYDROCHLORIDE
• NSC 23766
• N6-[2-(4-Diethylamino-1-methylbutylamino)-6-methylpyrimidin-4-yl]-2-methylquinoline-4,6-diamine tetrahydrochloride
• N6-(2-(5-(Diethylamino)pentan-2-ylamino)-6-methylpyrimidin-4-yl)-2-methylquinoline-4,6-diamine
• NSC23766;NSC 23766
• CS-1187
• CS-594
• NSC-23766 free base
• 4,6-Quinolinediamine, N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-
• NPEC-caged-(1S
• N6-(2-{[5-(ジエチルアミノ)ペンタン-2-イル]アミノ}-6-メチルピリミジン-4-イル)-2-メチルキノリン-4,6-ジアミン
• 6-[2-[[4-(ジエチルアミノ)-1-メチルブチル]アミノ]-6-メチル-4-ピリミジニルアミノ]-2-メチル-4-キノリンアミン
• NSC-23766