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5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン

5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン 化学構造式
251647-50-4
CAS番号.
251647-50-4
化学名:
5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン
别名:
5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン
英語名:
5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
英語别名:
N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide;N2-iBu-DMT-2'-O-MOE-Gr;N2-iBu-2'-MOE-5'-O-DMT-G;5'-O-DMTr-2'-O-MOE-rG(iBu);5'-O-DMTr-2'-O-MOE-rG(iBu);5'-O-DMT-2'-O-MOE-N2-ibu-rG;5'-ODMT-2'-OMOE-N-iBu Guanosine;5'-O-DMT-2’-MOE-N2-iBu-Guanosine;5'-O-DMT-2'-O-MOE-N2-isobutyryl-guanosine;5'-O-DMT-2'-O-(2-methoxyethyl)-N2-iBu-Guanosine
CBNumber:
CB71482846
化学式:
C38H43N5O9
分子量:
713.78
MOL File:
251647-50-4.mol

5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン 物理性質

融点 :
112.5-126.6 °C(Solv: hexane (110-54-3))
比重(密度) :
1.33±0.1 g/cm3(Predicted)
酸解離定数(Pka):
9.16±0.20(Predicted)
InChIKey:
XDLPRZLZAFJSMA-JKILKRELNA-N
SMILES:
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OCCOC)[C@@H]1O |&1:25,27,44,50,r|

安全性情報

5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン 価格 もっと(2)

メーカー 製品番号 製品説明 CAS番号 包装 価格 更新時間 購入
富士フイルム和光純薬株式会社(wako) W01TRCB490100 5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine 		251647-50-4 5mg ￥56900 2023-06-01 購入
富士フイルム和光純薬株式会社(wako) W01TRCB490100 5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン
5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine 		251647-50-4 50mg ￥451600 2023-06-01 購入

5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン 化学特性,用途語,生産方法

使用

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine is an oligonucleotide analogue which is being researched for the treatment of a wide variety of diseases, cancers, and conditions.

定義

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine is an antiviral monophosphate nucleoside. It is a modified nucleic acid analogue that acts as an activator of ribonucleotide reductase and DNA polymerase. The anticancer activity of this product may be due to its ability to inhibit the synthesis of diphosphate nucleotides.

5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン 上流と下流の製品情報

原材料

準備製品

5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン 生産企業

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  • 251647-50-4
  • N2-ISOBUTYRYL-5 , O-(4,4 -DIMETHOXYTRITYL)-2 -O-(2
  • 5'-O-[Bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-N-(2-Methyl-1-oxopropyl)guanosine
  • N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine
  • Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-
  • 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine
  • 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
  • N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
  • 5'-O-DMT-2’-MOE-N2-iBu-Guanosine
  • N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
  • 5'-O-DMT-2'-O-(2-methoxyethyl)-N2-iBu-Guanosine
  • 5'-O-DMTr-2'-O-MOE-rG(iBu)
  • N2-iso-Butyryl-5’-O-DMTr-2’-O-(2-methoxyethyl) guanosine
  • N2-ISOBUTYRYL-5 , O-(4,4 -DIMETHOXYTRITYL)-2 -O-
  • 5'-ODMT-2'-OMOE-N-iBu Guanosine
  • N2-iso-Butyryl-5’-O-DMTr-2’-O-(2-methoxyethyl) guanosine
  • 5'-O-DMT-2'-O-MOE-N2-isobutyryl-guanosine
  • 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine
  • 5'-O-DMT-2'-O-(2-methoxyethyl)-N2-iBu-Guanosine
  • 5'-O-DMT-2'-O-MOE-N2-ibu-rG
  • N2-iBu-2'-MOE-5'-O-DMT-G
  • N2-iBu-DMT-2'-O-MOE-Gr
  • 5'-O-DMTr-2'-O-MOE-rG(iBu)
  • 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N4-isobutyrylguanosine
  • 5'-O-[ビス(4-メトキシフェニル)フェニルメチル]-2'-O-(2-メトキシエチル)-N-(2-メチル-1-オキソプロピル)グアノシン
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