5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine Struktur
251647-50-4
CAS-Nr.
251647-50-4
Englisch Name:
5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
Synonyma:
N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide;N2-iBu-DMT-2'-O-MOE-Gr;N2-iBu-2'-MOE-5'-O-DMT-G;5'-O-DMTr-2'-O-MOE-rG(iBu);5'-O-DMTr-2'-O-MOE-rG(iBu);5'-O-DMT-2'-O-MOE-N2-ibu-rG;5'-ODMT-2'-OMOE-N-iBu Guanosine;5'-O-DMT-2’-MOE-N2-iBu-Guanosine;5'-O-DMT-2'-O-MOE-N2-isobutyryl-guanosine;5'-O-DMT-2'-O-(2-methoxyethyl)-N2-iBu-Guanosine
CBNumber:
CB71482846
Summenformel:
C38H43N5O9
Molgewicht:
713.78
MOL-Datei:
251647-50-4.mol

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine Eigenschaften

Schmelzpunkt:
112.5-126.6 °C(Solv: hexane (110-54-3))
Dichte
1.33±0.1 g/cm3(Predicted)
pka
9.16±0.20(Predicted)
InChIKey
XDLPRZLZAFJSMA-JKILKRELNA-N
SMILES
O(C(C1=CC=C(OC)C=C1)(C1=CC=C(OC)C=C1)C1=CC=CC=C1)C[C@H]1O[C@@H](N2C3=C(C(NC(=N3)NC(=O)C(C)C)=O)N=C2)[C@H](OCCOC)[C@@H]1O |&1:25,27,44,50,r|

Sicherheit

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine is an oligonucleotide analogue which is being researched for the treatment of a wide variety of diseases, cancers, and conditions.

Definition

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine is an antiviral monophosphate nucleoside. It is a modified nucleic acid analogue that acts as an activator of ribonucleotide reductase and DNA polymerase. The anticancer activity of this product may be due to its ability to inhibit the synthesis of diphosphate nucleotides.

5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

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  • N2-ISOBUTYRYL-5 , O-(4,4 -DIMETHOXYTRITYL)-2 -O-(2
  • 5'-O-[Bis(4-Methoxyphenyl)phenylMethyl]-2'-O-(2-Methoxyethyl)-N-(2-Methyl-1-oxopropyl)guanosine
  • N2-iso-Butyroyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)guanosine
  • Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)-
  • 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N2-isobutyrylguanosine
  • 5'-O-DMT-N2-isobutyryl-2'-O-(2-methoxyethyl)guanosine
  • N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxy-3-(2-methoxyethoxy)oxolan-2-yl]-6-oxo-3H-purin-2-yl]-2-methylpropanamide
  • 5'-O-DMT-2’-MOE-N2-iBu-Guanosine
  • N-(9-((2R,3R,4R,5R)-5-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-hydroxy-3-(2-methoxyethoxy)tetrahydrofuran-2-yl)-6-oxo-6,9-dihydro-1H-purin-2-yl)isobutyramide
  • 5'-O-DMT-2'-O-(2-methoxyethyl)-N2-iBu-Guanosine
  • 5'-O-DMTr-2'-O-MOE-rG(iBu)
  • N2-iso-Butyryl-5’-O-DMTr-2’-O-(2-methoxyethyl) guanosine
  • N2-ISOBUTYRYL-5 , O-(4,4 -DIMETHOXYTRITYL)-2 -O-
  • 5'-ODMT-2'-OMOE-N-iBu Guanosine
  • N2-iso-Butyryl-5’-O-DMTr-2’-O-(2-methoxyethyl) guanosine
  • 5'-O-DMT-2'-O-MOE-N2-isobutyryl-guanosine
  • 5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-2'-O-(2-methoxyethyl)-N-(2-methyl-1-oxopropyl)guanosine
  • 5'-O-DMT-2'-O-(2-methoxyethyl)-N2-iBu-Guanosine
  • 5'-O-DMT-2'-O-MOE-N2-ibu-rG
  • N2-iBu-2'-MOE-5'-O-DMT-G
  • N2-iBu-DMT-2'-O-MOE-Gr
  • 5'-O-DMTr-2'-O-MOE-rG(iBu)
  • 5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-O-(2-methoxyethyl)-N4-isobutyrylguanosine
  • 251647-50-4
  • Amines, Aromatics, Pharmaceuticals, Intermediates & Fine Chemicals
  • Modified(deoxy)nucleoside
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