1,3-ジフェニル-1,3-プロパンジオン 化学特性,用途語,生産方法
外観
白色～うすい黄色～うすい黄赤色粉末～結晶
溶解性
エタノールに溶けやすく、水にほとんど溶けない。
解説
ジベンゾイルメタン略称DBM．エノール形，ケト形が存在する．カルコンの二臭化物にナトリウムメトキシドを作用させ，ついで塩酸と加熱すると得られる．ケト形は融点81 ℃．エノール形は融点72 ℃(Z形)および78 ℃(E形)がある．沸点219～221 ℃(2.4 kPa)．種々の金属イオンとキレート錯イオンを生じ，これらの抽出剤として使用できる．とくにEDTAと併用してウラン(Ⅵ)の選択的抽出や，Cdの分離に用いられる．
用途
有機合成原料、金属の抽出，分離用キレート剤、ウランの吸光光度法による発色試薬。
化学的特性
Dibenzoylmethane (DB), a minor constituent of the root extract of licorice, belongs to the flavonoid family. It is a colorless rhombus flake crystal or yellowish-white powder. soluble in chlorohydrin and chloroform, soluble in sodium hydroxide solution, insoluble in sodium carbonate solution, and very slightly soluble in water. It is used as a colorimetric reagent for the determination of uranium.
天然物の起源
Dibenzoylmethane(DBM) is a 1,3-diketone derivative of acetylacetone that has both methyl groups replaced with phenyl groups.Although smaller in size and lacking hydroxyl and methoxy groups，DBM resembles the turmeric spice curcumin (CUR),a diferuloylmethane. Both molecules are metal-chelating agents，contain a B-diketone flanked by two aryl groups,and exhibit anti-proliferative and anticarcinogenic activity. In addition to sharing structural similarity with DBM,CUR,which is also a naturally occurring compound is found in the plant Curcuma longa and has numerous medicinal uses.
DBM and its many naturally occurring derivatives are minor constituentsof licorice. DBM has been isolated from licorice root extracts and otherspecies of Glycyrrhiza.
使用
Dibenzoylmethane is a new kind of PVC heat stabilizer, it has better transparency, nontoxic and odorless. In case of combined use with Calcium/Zinc, Barium/Zin and other heat stabilizer, it can greatly improve the initial color, transparency, long term stability of PVC, and also can improve the precipitation and “zinc burning” problem during the process. It has very good synergy with zinc soaps, and can protect the PVC color. This material can absorb UV at 290nm, which has the effect as light stabilizer and act as long term stabilizer for PVC products.
定義
ChEBI: Dibenzoylmethane is a beta-diketone that is acetylacetone (acac) in which both methyl groups have been replaced by phenyl groups. It is a minor constituent of the root extract of licorice (Glycyrrhiza glabra) and exhibits antimutagenic and anticancer effects. It has a role as an antineoplastic agent, a metabolite and an antimutagen. It is a beta-diketone and an aromatic ketone.
製造方法
dibenzoylmethane is prepared by condensation of ethyl benzoate with acetophenone.
安全性プロファイル
Moderately toxic by ingestion. When heated to decomposition it emits acrid smoke and irritating vapors
純化方法
Dibenzoylmethane (1,3-diphenyl-1,3-propanedione) [120-46-7] M 224.3, m 8 0o. Crystallise dibenzoylmethane from pet ether or MeOH. [Beilstein 7 IV 2512.]
1,3-ジフェニル-1,3-プロパンジオン 上流と下流の製品情報
原材料
準備製品